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TP53 BRCA1 CRISPR single-cell cancer

Lau(Albert Y),Chasman(Daniel I) Proc Natl Acad Sci U S A 2004-07-16

...BRCA2, and WT1. We examine protein variants caused by nonsynonymous single-nucleotide polymorphisms in a set of clinical...

Ahn(Sei Hyun),Hwang(Ui Kang),Kwak(Beom Seo... J Korean Med Sci 2004-07-13

...BRCA2 genes were analyzed by Conformation-Sensitive Gel Electrophoresis (CSGE), and any aberrantly-sized band was sequen...

Olivier(R I),van Beurden(M),Lubsen(M A C),... Br J Cancer 2004-05-26

...BRCA2 and nine HBOC, respectively). A total of 90 women underwent bilateral salpingo-oophorectomy (58 BRCA1, six BRCA2, ...

Foulkes(William D),Metcalfe(Kelly),Sun(Pin... Clin Cancer Res 2004-12-21

BRCA1-related breast cancers are more frequently estrogen receptor (ER) negative than are either BRCA2-related or nonher...

Lakhani(Sunil R),Manek(Sanjiv),Penault-Llo... Clin Cancer Res 2004-12-16

Germline mutations in the BRCA1 and BRCA2 genes confer increased susceptibility to ovarian cancer. There is evidence tha...

Lowenfels(Albert B),Maisonneuve(Patrick) Jpn J Clin Oncol 2004-08-05

...BRCA2 mutations are the commonest inherited disorder. In addition to germline defects, there are several common polymorp...

Mikaelsdottir(Evgenia K),Valgeirsdottir(Si... Breast Cancer Res 2004-11-04

...BRCA2 gene (BRCA2 999del5) accounts for 7-8% of female breast cancers and for 40% of male breast cancers in Iceland. If ...

Campbell(Ian G),Choong(David),Chenevix-Tre... Breast Cancer Res 2004-11-04

Mutations in BRCA1, BRCA2, ATM, TP53, CHK2 and PTEN account for many, but not all, multiple-case breast and ovarian canc...

Shin(Min Sun),Fredrickson(Torgny N),Hartle... Cancer Res 2004-08-26

...Brca2, Snf1lk, Nfkb1, Pou2af1, Prdm1, Stat6, and Blnk. Heightened expression of Gfi1 distinguishes MZL from other lympho...

Daniels(Douglas S),Woo(Tammy T),Luu(Kieu X... Nat Struct Mol Biol 2004-09-16

...BRCA2. Structural and biochemical results further support an unpredicted role for Tyr114 in nucleotide flipping through ...

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