...BRCA2-deficient cells. We also identify biallelic inactivating mutations in DDIAS in patients with a severe neurodevelop...
...BRCA2 (gBRCApv) germline variants and high-risk human epidermal growth factor receptor 2 (HER2)-negative early breast ca...
...BRCA2 Variant Curation Expert Panel American College of Medical Genetics and Genomics (ACMG)/Association for Molecular P...
...BRCA2, ataxia telangiectasia mutated, and checkpoint kinase 2), are prevalent in ovarian, endometrial, and breast cancer...
...BRCA2, and ATM genes. All treatment groups exhibited significant reductions in PSA and testosterone levels. Leuprolide 2...
...BRCA2, ATM) and were enriched in pathways related to TP53 signalling, homologous recombination repair, and oncogenic sig...
As a highly radiation-resistant microbial BRCA2 organism, Ustilago maydis is an attractive genetic system to study the m...
...BRCA2-mutated mHSPC. Positive results have also recently been obtained from the phase III TALAPRO-3 trial; talazoparib a...
...BRCA2). Incidence was lowest within the first 5 years (0.88%/year) and increased beyond 10 years (1.89%/year). These est...
...BRCA2 (4.6%) and ATM (3.1%). P/LP variants were identified in 6.8% of patients who did not meet classical referral crite...
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