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TP53 BRCA1 CRISPR single-cell cancer

Stark(Jeremy M),Pierce(Andrew J),Oh(Jin),P... Mol Cell Biol 2004-12-03

...BRCA2 was impaired, i.e., HDR was reduced but SSA was increased. In particular, expression of an ATP-binding mutant of R...

Bunyan(D J),Eccles(D M),Sillibourne(J),Wil... Br J Cancer 2004-11-26

...BRCA2 in families with hereditary breast/ovarian cancer (BRCA) and APC in patients with familial adenomatous polyposis c...

Esplen(Mary Jane),Hunter(Jon),Leszcz(Molyn... Cancer 2004-12-22

Women with a BRCA1/BRCA2 mutation experience significant challenges. These include decision-making regarding surgical op...

Hamilton(L J),Evans(A J),Wilson(A R M),Sco... Clin Radiol 2004-10-28

...BRCA2-associated breast carcinoma.,Family history clinic records identified 18 BRCA1 and 10 BRCA2 cases who collectively...

Turner(Nicholas),Tutt(Andrew),Ashworth(Ala... Nat Rev Cancer 2004-11-19

Germline mutations in the BRCA1, BRCA2 and Fanconi anaemia genes confer cancer susceptibility, and the proteins encoded ...

Menkiszak(J),Rzepka-Górska(I),Górski(B),Gr... Eur J Gynaecol Oncol 2004-06-15

...BRCA2 susceptibility genes is performed throughout Europe and North America. In Poland three founder mutations in BRCA1 ...

Menkiszak(J),Gronwald(J),Górski(B),Byrski(... Eur J Gynaecol Oncol 2004-06-15

...BRCA2 gene.,303 patients with ovarian cancer were reviewed for clinical features and for cancer family histories. After ...

Okobia(M N),Bunker(C H) Afr J Reprod Health 2004-04-22

...BRCA2 and p53 confer a high risk for an individual, they represent a low overall attributable risk due to low allele fre...

Nkondjock(André),Ghadirian(Parviz) Cancer Lett 2004-04-28

...BRCA2 have been associated with an increased lifetime risk of breast and ovarian cancers. Many of the well-recognized ri...

Menkiszak(Janusz),Brzosko(Marek),Górski(Bo... J Appl Genet 2004-06-29

The study aimed to determine whether hereditary ovarian cancers that are not caused by BRCA1/BRCA2 constitutional mutati...

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