Inherited mutations of the BRCA2 gene give rise to a multi-site cancer phenotype which includes breast cancer (in female...
...BRCA2 in high-risk non-Ashkenazi Jews. In a Libyan family the 1100delAT BRCA1 mutation was detected and the 8765delAG BR...
...BRCA2 compared with 28 (1.9%) controls. After adjusting for age, the presence of a BRCA1 or BRCA2 mutation was associate...
...BRCA2 mutation spectrum and the frequencies of deleterious alleles in various ethnic groups; (2) investigations on how i...
...BRCA2 can largely be accounted for by different methodologies and by studying research vs nonresearch families. In our j...
...BRCA2, C112R (E4) and R158C (E2) in ApoE and C825T in GNB3, did not show any sign of association. The P187S polymorphism...
Variation in the penetrance estimates for BRCA1 and BRCA2 mutation carriers suggests that other genetic polymorphisms ma...
...BRCA2, and p53, all of which are important in the development of pancreatic carcinoma and frequently are involved in a v...
...BRCA2 by complete sequencing. Family history through three generations was obtained. Available paraffin-embedded tissue ...
...BRCA2 carrier. In each case, nontumor tissue areas surrounding the tumor or from other locations of the breast were isol...
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