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Conservative management of breast cancer in BRCA1/2 mutation carriers.

Alpert(Tracy E),Haffty(Bruce G) Clin Breast Cancer 2004-07-29

...BRCA2 remains controversial. These breast cancer susceptibility genes are associated with a progressive risk of second c...

Diagnostic genetic testing for hereditary breast and ovarian cancer in cancer...

Claes(Erna),Evers-Kiebooms(Gerry),Boogaert... Genet Test 2004-11-24

...BRCA2 mutation carriers, 7 noncarriers, and 36 patients with an inconclusive genetic test result. Cancer patients had a ...

Estrogen receptor status in BRCA1- and BRCA2-related breast cancer: the influ...

Foulkes(William D),Metcalfe(Kelly),Sun(Pin... Clin Cancer Res 2004-12-21

BRCA1-related breast cancers are more frequently estrogen receptor (ER) negative than are either BRCA2-related or nonher...

Recent developments in ovarian cancer genetics.

Barnett(Ginger L),Friedrich(Christopher A) Curr Opin Obstet Gynecol 2004-06-03

...BRCA2 mutation spectrum and the frequencies of deleterious alleles in various ethnic groups; (2) investigations on how i...

Ovarian cystadenoma as a characteristic feature of families with hereditary o...

Menkiszak(Janusz),Brzosko(Marek),Górski(Bo... J Appl Genet 2004-06-29

The study aimed to determine whether hereditary ovarian cancers that are not caused by BRCA1/BRCA2 constitutional mutati...

Cancer variation associated with the position of the mutation in the BRCA2 gene.

Lubinski(Jan),Phelan(Catherine M),Ghadiria... Fam Cancer 2004-07-22

Inherited mutations of the BRCA2 gene give rise to a multi-site cancer phenotype which includes breast cancer (in female...

The 1100delAT BRCA1 and the 8765delAG BRCA2 mutations: occurrence in high-ris...

Gal(Inbar),Gershoni Baruch(Ruth),Haber(Dan... Fam Cancer 2004-07-22

...BRCA2 in high-risk non-Ashkenazi Jews. In a Libyan family the 1100delAT BRCA1 mutation was detected and the 8765delAG BR...

BRCA mutations and risk of prostate cancer in Ashkenazi Jews.

Kirchhoff(Tomas),Kauff(Noah D),Mitra(Nandi... Clin Cancer Res 2004-11-10

...BRCA2 compared with 28 (1.9%) controls. After adjusting for age, the presence of a BRCA1 or BRCA2 mutation was associate...

A screen for germline mutations in the gene encoding CCCTC-binding factor (CT...

Zhou(Xiao-Lei),Werelius(Barbro),Lindblom(A... Breast Cancer Res 2004-07-27

...BRCA2 breast cancer for germline mutations in the CTCF gene.,Mutation screening of CTCF was performed by denaturing high...

Study design: evaluating gene-environment interactions in the etiology of bre...

Bernstein(Jonine L),Langholz(Bryan),Haile(... Breast Cancer Res 2004-07-27

...BRCA2) encode products that are essential for the normal cellular response to DSBs, but predispose to breast cancer when...

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