...BRCA2-mutations can cause Fanconi anemia and are found in approximately 7% of pancreatic cancers. Recently, several sequ...
...BRCA2 function, and structural and biochemical advances shed new light on the interactions between BRCA2, the RAD51 reco...
...BRCA2 binding protein, EMSY, as a putative oncogene implicates the BRCA2 pathway in sporadic tumors. Furthermore, EMSY's...
...BRCA2 gene product, we found that a deubiquitinating enzyme, USP11, formed specific complexes with BRCA2. Moreover, BRCA...
...BRCA2) than HPV-negative samples. Our results suggest that different genetic pathways of carcinogenesis may be associate...
...BRCA2, in 1994 and 1995 and the subsequent development of commercial genetic testing has brought hereditary cancer genet...
...BRCA2. The evidence strongly suggests that two variants (C1787S in BRCA1 and D2723H in BRCA2) are deleterious, three (R8...
...BRCA2, MLH1, and MSH2 was performed. Eighty-seven healthy women were tested for known family mutations and self-assessme...
...BRCA2, MLH1, MSH2, TP53, and PTEN, is becoming an increasingly important part of clinical practice. Interpretation of tr...
...BRCA2 (BRCA1/2), are associated with predisposition for inherited breast and ovarian cancer and are identified in 5%-10%...
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