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Characterization of the molecular and clinical features of Multilocus Inherit...

Akcan(MB),Duru(A),Erdoğan(KM),Özer Kaya(Ö)... Fam Cancer 2026-06-08

...RCA2-CHEK2 (n = 6). Notably, CNVs were identified in 7% of cases, highlighting the necessity of structural variant analy...

More harm than good? The UK National Screening Committee's latest review of p...

Boshari(T),Anderson(A),Richards(M) BJU Int 2026-06-08

...BRCA2 variant with a family history of breast, ovarian, pancreatic, or prostate cancer. This was the only group where th...

Impact of homologous recombination repair gene mutations on survival in metas...

Cancel-Tassin(G),Kariyawasam(T),Gautier(L)... Fr J Urol 2026-08-00

...BRCA2-mutated patients exhibited a reduced median OS of 24.0months (95% CI: 9.0-40.0; P=0.036) and a faster progression-...

The 'Prostate Cancer Screening for People at Genetic Risk of Aggressive Disea...

Cheng(HH),Maxwell(KN),Salari(K),Cooperberg... BJU Int 2026-06-09

...BRCA2, HOXB13, ATM, BRCA1, MSH2, MSH6, CHEK2 and TP53. However, the optimal early detection strategy for gPV carriers, i...

Longitudinal Association of Quantitative Background Parenchymal Enhancement w...

Nguyen(AA),Cohen(EA),Ehsan(S),Mankowski(WC... Cancer Epidemiol Biomarkers... 2026-06-10

...BRCA2, HR=1.13, p<0.005, both measures HR per 10 units). Association was stronger in axial MRIs in both models (smaller:...

Implementation of Genetic Testing in Prostate Cancer: A Real-World Survey of ...

Kaulfuss(JC),Jeutner(J),Erber(B),Siech(C),... Cancers (Basel) 2026-06-23

...BRCA2 were recognized by 96.6% of respondents. Knowledge of other PC-associated genes was much lower. Conclusions: Despi...

Genomic Variability of the HCT116 Cell Line Identified Using Oxford Nanopore ...

Mikheeva(R),Leonov(P),Koryukov(M),Ruleva(E... Int J Mol Sci 2026-06-26

...BRCA2. However, its landscape of large genomic rearrangements (LGRs) and copy number variants (CNVs) is still far from b...

A Bayesian framework for longitudinal EHR and genetic discovery.

Urbut(SM),Ding(Y),Nakao(T),Koyama(S),Misra... Nature 2026-08-00

...BRCA2 (refs. 7,8) aligns with disease specificities. A signature-based genome-wide association study identifies 151 geno...

Monoallelic BRCA1/2 variants in pediatric, adolescent, and young adult patien...

Cipri(S),Agolini(E),Baldo(GD),Cacchione(A)... ESMO Open 2026-08-00

...BRCA2 DNA repair associated (BRCA2), two key DNA repair genes, are strongly linked to adult-onset malignancies and play ...

Next-generation sequencing-based characterization of BRCA1/2 variants across ...

Nguyen(HT),Vu(MD),Nguyen(DD),Dinh(PN),Hoan... BMC Cancer 2026-07-17

...BRCA2 (40/57 BRCA1 vs 17/57 BRCA2 in ovarian cancer and 57/78 BRCA1 vs 21/78 BRCA2 in TNBC). Several BRCA1 truncating va...

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