...RCA2-CHEK2 (n = 6). Notably, CNVs were identified in 7% of cases, highlighting the necessity of structural variant analy...
...BRCA2 variant with a family history of breast, ovarian, pancreatic, or prostate cancer. This was the only group where th...
...BRCA2-mutated patients exhibited a reduced median OS of 24.0months (95% CI: 9.0-40.0; P=0.036) and a faster progression-...
...BRCA2, HOXB13, ATM, BRCA1, MSH2, MSH6, CHEK2 and TP53. However, the optimal early detection strategy for gPV carriers, i...
...BRCA2, HR=1.13, p<0.005, both measures HR per 10 units). Association was stronger in axial MRIs in both models (smaller:...
...BRCA2 were recognized by 96.6% of respondents. Knowledge of other PC-associated genes was much lower. Conclusions: Despi...
...BRCA2. However, its landscape of large genomic rearrangements (LGRs) and copy number variants (CNVs) is still far from b...
...BRCA2 (refs. 7,8) aligns with disease specificities. A signature-based genome-wide association study identifies 151 geno...
...BRCA2 DNA repair associated (BRCA2), two key DNA repair genes, are strongly linked to adult-onset malignancies and play ...
...BRCA2 (40/57 BRCA1 vs 17/57 BRCA2 in ovarian cancer and 57/78 BRCA1 vs 21/78 BRCA2 in TNBC). Several BRCA1 truncating va...
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