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TP53 BRCA1 CRISPR single-cell cancer

Tischkowitz(M D),Morgan(N V),Grimwade(D),E... Leukemia 2004-03-24

...BRCA2). Mutations in the FANCA gene are the most prevalent, accounting for two-thirds of FA cases. Affected individuals ...

Blom(Eric),van de Vrugt(Henri J),de Vries(... DNA Repair (Amst) 2004-08-26

...BRCA2. A key step in the pathway involves the monoubiquitylation of FANCD2, which critically depends on a multi-subunit ...

Pastoriza Gallego(Manuela),Sarasin(Alain) Biochimie 2004-09-17

...BRCA2 and MSH2 proteins. The lack of TCR of oxidative lesions may lead to dramatic hereditary diseases like Cockayne syn...

Kojic(Milorad),Holloman(William K) Cell Cycle 2004-12-27

The tumor suppressor BRCA2 plays an essential role in the repair of double-strand DNA breaks by regulating the action of...

Rogers(Carmelle D),van der Heijden(Michiel... Cancer Biol Ther 2004-11-19

...BRCA2 gene. Since carriers of germline BRCA2 gene mutations have an increased risk of developing pancreatic cancer, the ...

Meng(Xiangbing),Liu(Jingmei),Shen(Zhiyuan) Cell Cycle 2004-12-27

The BCCIP alpha protein was identified as a BRCA2 and CDKN1A (p21, or p21(Waf1/Cip1)) Interacting Protein. It binds to a...

Bennett(I C),Gattas(M),Teh(B T) Breast 2004-01-23

...BRCA2, ATM gene, PTEN and p53. Several other less frequently occurring predisposition genes such as the androgen recepto...

Mote(Patricia A),Leary(Jennifer A),Avery(K... Genes Chromosomes Cancer 2004-03-16

...BRCA2 mutation carriers. The alterations in PS2 and PR expression were similar in the BRCA1 and BRCA2 carriers, demonstr...

van Geel(A N) Breast 2004-05-04

...BRCA2 mutation patients seems to be similar to that in sporadic cancer. The most striking result of PM is the decrease o...

Shannon(C),Smith(I E) Eur J Cancer 2004-01-27

...BRCA2, TP53, PTEN or who have previously received mantle irradiation for Hodgkin's disease need close follow-up and are ...

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