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Alternatively spliced, truncated human BRCA2 isoforms contain a novel coding ...

Speevak(Marsha D),Young(Sean S),Feilotter(... Eur J Hum Genet 2004-08-19

...BRCA2 was discovered in leucocytes from high-risk breast cancer patients. Although sequencing of the genomic DNA in this...

A high frequency of BRCA2 gene mutations in Polish families with ovarian and ...

Jakubowska(Anna),Scott(Rodney),Menkiszak(J... Eur J Hum Genet 2004-08-19

...BRCA2 mutation in Polish patients with ovarian cancer. A BRCA2 mutation was found in eight of 34 women with ovarian canc...

Phosphorylation of BRCA2 by the Polo-like kinase Plk1 is regulated by DNA dam...

Lee(MiYoung),Daniels(Matthew J),Venkitaram... Oncogene 2004-03-02

...BRCA2 modification. BRCA2 and Plk1 interact with one another in cell lysates, through a conserved region in BRCA2, which...

Inactivation of the Fanconi anemia/BRCA pathway in lung and oral cancers: imp...

Marsit(Carmen J),Liu(Mei),Nelson(Heather H... Oncogene 2004-03-02

...BRCA2 was detected. FANCF methylation was associated with a shorter duration of tobacco use (P=0.03) and a younger age o...

Evaluation of BRCA2 in the genetic susceptibility of familial esophageal cancer.

Hu(Nan),Wang(Chaoyu),Han(Xiao-You),He(Li-J... Oncogene 2004-03-03

...BRCA2 in ESCC patients from this high-risk area of China are more frequent in FH+ than FH- cases, suggesting that BRCA2 ...

Fidelity of DNA double-strand break repair in heterozygous cell lines harbour...

Coupier(Isabelle),Baldeyron(Céline),Rousse... Oncogene 2004-03-02

...BRCA2 genes, when they lead to a truncated protein, confer a high risk of breast and ovarian cancer. However, the role o...

Enhanced sensitivity of peripheral blood lymphocytes from women carrying a BR...

Trenz(Kristina),Lugowski(Sebastian),Jahrsd... Mutat Res 2004-01-21

...BRCA2. Our previous results indicated a close relationship between the presence of a BRCA1 mutation and sensitivity for ...

One in 10 ovarian cancer patients carry germ line BRCA1 or BRCA2 mutations: r...

Malander(S),Ridderheim(M),Måsbäck(A),Loman... Eur J Cancer 2004-02-27

...BRCA2 in one case. Four additional missense variants (one in BRCA1 and three in BRCA2) with a possible association with ...

Loss of heterozygosity on chromosome 13q: suggestion of a candidate tumor sup...

Tong(Dan),Schuster(Eva),Czerwenka(Klaus),L... Breast Cancer Res Treat 2004-05-13

...BRCA2, but is also attributable to another gene in this region. There is strong indication of a new tumor suppressor gen...

Heteroduplex-based genotyping with microchip electrophoresis and dHPLC.

Footz(Tim),Somerville(Martin J),Tomaszewsk... Genet Test 2004-10-21

...BRCA2 with, as additional examples, 188del11 and 5396 + 1G --> A in BRCA1. Our HA method is based upon the use of a repl...

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