Women with a BRCA1/BRCA2 mutation experience significant challenges. These include decision-making regarding surgical op...
...BRCA2 mutation, can present itself with ovarian cancer only. In three women, 43, 50 and 61 years of age, there was a fam...
There is emerging evidence from clinical and experimental data that familial breast cancers, including BRCA1 and BRCA2 r...
Several genes conferring susceptibility to breast and ovarian cancer, notably BRCA1 and BRCA2, have been identified. The...
...BRCA2 genes was identified in 20% of the probands. Seventy primary breast cancer cases were recorded since the onset of ...
...BRCA2 carriers (RR=0.38, 95%CI: 0.06-1.56). In BRCA1 or BRCA2 carriers with breast cancer, tamoxifen use was associated ...
...BRCA2 attributed to common founders. Here we report the frequency of previously described mutations (n = 7) and 13 mutat...
...BRCA2 are involved in DNA repair. To evaluate further the role of DNA repair in breast cancer we determined: (1) the kin...
Germline mutations in BRCA1 and BRCA2 predispose to breast and ovarian cancer. A multitude of mutations have been descri...
...BRCA2 genes (BReast CAncer 1/2). The BRCA1 protein is expressed ubiquitously and is likely to play a role in several fun...
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