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TP53 BRCA1 CRISPR single-cell cancer

Denic(Srdjan),Al-Gazali(Lihadh) Int J Mol Med 2003-05-14

...BRCA2 homozygotes die as embryos. Because tumor suppressor genes are conserved and less species-specific than other gene...

Zdzienicka(Malgorzata Z),Arwert(Fré) Trends Mol Med 2003-04-17

Surprisingly, biallelic mutations in the BRCA2 breast-cancer-susceptibility gene were found in Fanconi anemia (FA), a ra...

Phelan(Catherine M),Kwan(Elaine),Jack(Elai... Hum Mutat 2003-01-03

...BRCA2. Founder mutations were identified in 85 families (185delAG in 44 families, 5382insC in 16 families, and the BRCA2...

Kutler(David I),Singh(Bhuvanesh),Satagopan... Blood 2003-03-13

...BRCA2 (identified as FANCD1) with other known FA proteins suggests that FA proteins have a significant role in DNA repai...

Dagan(Efrat),Friedman(Eitan),Paperna(Tamar... Eur J Hum Genet 2003-06-10

...BRCA2 mutation, 149 had breast and/or ovarian cancer and 78 were asymptomatic mutation carriers. The mean age at diagnos...

Buchholz(Thomas A),Wazer(David E) Semin Radiat Oncol 2003-01-02

...BRCA2, PTEN, or ATM, or epigenetic functional inactivation of other tumor suppressor genes, such as SYK and NES1, appear...

Xia(Fen),Powell(Simon N) Semin Radiat Oncol 2003-01-02

...BRCA2, determine the phenotype of the tumor, with BRCA1- or BRCA2-deficient tumors showing marked sensitivity to ionizin...

Pierce(Lori) Semin Radiat Oncol 2003-01-02

...BRCA2 mutations has been questioned. This article reviews the data regarding radiation-associated complications in BRCA1...

Robson(Mark E),Offit(Kenneth) Semin Radiat Oncol 2003-01-02

...BRCA2 are the most commonly identified germline changes. Recognition of hereditary breast cancer is critical to allow th...

Velasco Sampedro(Eladio),Esteban Cardeñosa... Med Clin (Barc) 2003-01-28

...BRCA2 genes causing a predisposition. In the present study we analyzed BRCA1 and BRCA2 mutations in moderate to high ris...

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