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Chromosome breakage syndromes and cancer.

Duker(Nahum J) Am J Med Genet 2003-05-09

...BRCA2 genes. The cloning of the encoding genes and the characterization of their products have resulted in partial under...

Genetic counseling in hereditary breast/ovarian cancer in Israel: psychosocia...

DiCastro(Michal),Frydman(Moshe),Friedman(I... Am J Med Genet 2003-01-31

...BRCA2 genes. The long-term psychosocial impact of oncogenetic counseling on consultees and the retention of oncogenetic ...

Germline mutations in the BRCA1 gene predisposing to breast and ovarian cance...

Grzybowska(Ewa),Siemińska(Marzena),Zientek... Acta Biochim Pol 2003-10-07

Germline mutations in the BRCA1 or BRCA2 genes predispose their carriers to breast or/and ovary cancers during their lif...

Testing for BRCA1 mutations: a cost-effectiveness analysis.

Sevilla(Christine),Moatti(Jean-Paul),Julia... Eur J Hum Genet 2003-03-17

...BRCA2 mutations. Due to the diagnostic strategy used by the patent owner, Direct DNA sequencing (DS) may become the only...

Novel mutations in the BRCA1 and BRCA2 genes in Iranian women with early-onse...

Yassaee(Vahid R),Zeinali(Sirous),Harirchi(... Breast Cancer Res 2003-02-04

...BRCA2 genes. We analysed BRCA1 exons 11 and BRCA2 exons 10 and 11 by the protein truncation test, and BRCA1 exons 2, 3, ...

Histopathologic features of genetically determined ovarian cancer.

Shaw(P A),McLaughlin(J R),Zweemer(R P),Nar... Int J Gynecol Pathol 2003-03-03

...BRCA2. Thirty-two ovarian carcinomas associated with germline BRCA1 or BRCA2 mutations and 40 ovarian carcinomas from pa...

p53 mediates repression of the BRCA2 promoter and down-regulation of BRCA2 mR...

Wu(Kangjian),Jiang(Shi-Wen),Couch(Fergus J... J Biol Chem 2003-06-17

...BRCA2 mRNA and protein levels by altering both BRCA2 mRNA stability and protein stability. Thus, BRCA2 levels in the cel...

Molecular classification of familial non-BRCA1/BRCA2 breast cancer.

Hedenfalk(Ingrid),Ringner(Markus),Ben-Dor(... Proc Natl Acad Sci U S A 2003-05-13

In the decade since their discovery, the two major breast cancer susceptibility genes BRCA1 and BRCA2, have been shown c...

Average age-specific cumulative risk of breast cancer according to type and s...

Scott(Clare L),Jenkins(Mark A),Southey(Mel... Hum Genet 2003-06-18

...BRCA2 had been identified (28 and 23 families, respectively). Breast cancer risk in carriers was estimated under maximum...

Variants in CHEK2 other than 1100delC do not make a major contribution to bre...

Schutte(Mieke),Seal(Sheila),Barfoot(Rita),... Am J Hum Genet 2003-05-05

...BRCA2 mutations. To investigate whether other CHEK2 variants confer susceptibility to breast cancer, we screened the ful...

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