Surprisingly, biallelic mutations in the BRCA2 breast-cancer-susceptibility gene were found in Fanconi anemia (FA), a ra...
...BRCA2, PTEN, or ATM, or epigenetic functional inactivation of other tumor suppressor genes, such as SYK and NES1, appear...
...BRCA2, determine the phenotype of the tumor, with BRCA1- or BRCA2-deficient tumors showing marked sensitivity to ionizin...
...BRCA2 mutations has been questioned. This article reviews the data regarding radiation-associated complications in BRCA1...
...BRCA2 are the most commonly identified germline changes. Recognition of hereditary breast cancer is critical to allow th...
...BRCA2 (identified as FANCD1) with other known FA proteins suggests that FA proteins have a significant role in DNA repai...
...BRCA2 mutations. Some of the p53 mutants identified in BRCA1 and BRCA2 mutation carriers are either previously undescrib...
...BRCA2 had been identified (28 and 23 families, respectively). Breast cancer risk in carriers was estimated under maximum...
...BRCA2 appear to be rare in tumors of the pancreas. The mechanism by which mutant BRCA2 contributes to development of pan...
...BRCA2 mutations) can be determined. Recent developments have reinforced the clinical importance of breast cancer risk as...
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