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Disruption of the Fanconi anemia-BRCA pathway in cisplatin-sensitive ovarian ...

Taniguchi(Toshiyasu),Tischkowitz(Marc),Ame... Nat Med 2003-06-26

...BRCA2 (FANCD1). Here we show that the FANC-BRCA pathway is disrupted in a subset of ovarian tumor lines. Mono-ubiquitina...

Attitudes and psychological impact of genetic testing, genetic counseling, an...

Hutson(Sadie Pauline) Oncol Nurs Forum 2003-09-16

...BRCA2, researchers have studied some of the initial psychosocial effects of genetic information on women at high risk.,W...

Familial risks, early-onset breast cancer, and BRCA1 and BRCA2 germline mutat...

Dite(Gillian S),Jenkins(Mark A),Southey(Me... J Natl Cancer Inst 2003-04-11

...BRCA2-related.,Mutations in genes other than BRCA1 and BRCA2 may be associated with a high risk of breast cancer, especi...

CYP17 promoter polymorphism and breast cancer risk in males and females in re...

Gudmundsdottir(K),Thorlacius(S),Jonasson(J... Br J Cancer 2003-05-05

...BRCA2 mutation. The study population consisted of 39 male and 523 female breast cancer cases and 309 male and 395 female...

Epithelial lesions in prophylactic mastectomy specimens from women with BRCA ...

Kauff(Noah D),Brogi(Edi),Scheuer(Lauren),P... Cancer 2003-04-16

...BRCA2 mutation who participated in an ongoing follow-up study and underwent PM at Memorial Sloan-Kettering Cancer Center...

Germline mutations in the BRCA1 and BRCA2 genes in Turkish breast/ovarian can...

Manguoglu(A Esra),Lüleci(Güven),Ozçelik(Ta... Hum Mutat 2003-04-18

In this study we genotyped Turkish breast/ovarian cancer patients for BRCA1/BRCA2 mutations: protein truncation test (PT...

Mutational analysis of BRCA2 in Spanish breast cancer patients from Castilla-...

Duran(Mercedes),Esteban-Cardeñosa(Eva),Vel... Hum Mutat 2003-04-18

Mutations in BRCA1 and BRCA2 account for approximately 5% of the overall familial risk of breast cancer. We have carried...

Haplotype analysis of the BRCA2 9254delATCAT recurrent mutation in breast/ova...

Campos(Berta),Díez(Orland),Odefrey(Fabrice... Hum Mutat 2003-04-18

...BRCA2 polymorphisms were used for the haplotype analyses. The markers were located flanking the BRCA2 gene spanning a re...

Molecular classification of breast carcinomas by comparative genomic hybridiz...

Wessels(Lodewyk F A),van Welsem(Tibor),Har... Cancer Res 2003-01-07

In approximately 70% of the families with a high frequency of early-onset breast and/or ovarian cancer, BRCA1 or BRCA2 g...

BRCA2 founder mutation in Slovenian breast cancer families.

Krajc(Mateja),De Grève(Jacques),Goelen(Gui... Eur J Hum Genet 2003-08-26

Linkage analysis has identified BRCA1 and BRCA2 germline mutations as the major cause for cancer predisposition in breas...

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