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[Clinical and molecular diagnosis of inherited breast-ovarian cancer].

Chompret(A) J Gynecol Obstet Biol Repro... 2003-06-10

...BRCA2, which confer a high risk of developing BC and ovarian cancer (OC), are likely to account for most families with m...

Diagnostic imaging in the clinical management of patients at high risk for br...

Pastore(Giovanna),Canadè(Adolfo),Costantin... Rays 2003-05-01

...BRCA2) have already been identified. At present, genetic tests to identify known inherited mutations associated with bre...

Epithelial lesions in prophylactic mastectomy specimens from women with BRCA ...

Kauff(Noah D),Brogi(Edi),Scheuer(Lauren),P... Cancer 2003-04-16

...BRCA2 mutation who participated in an ongoing follow-up study and underwent PM at Memorial Sloan-Kettering Cancer Center...

Germline mutations in the BRCA1 and BRCA2 genes in Turkish breast/ovarian can...

Manguoglu(A Esra),Lüleci(Güven),Ozçelik(Ta... Hum Mutat 2003-04-18

In this study we genotyped Turkish breast/ovarian cancer patients for BRCA1/BRCA2 mutations: protein truncation test (PT...

Mutational analysis of BRCA2 in Spanish breast cancer patients from Castilla-...

Duran(Mercedes),Esteban-Cardeñosa(Eva),Vel... Hum Mutat 2003-04-18

Mutations in BRCA1 and BRCA2 account for approximately 5% of the overall familial risk of breast cancer. We have carried...

Haplotype analysis of the BRCA2 9254delATCAT recurrent mutation in breast/ova...

Campos(Berta),Díez(Orland),Odefrey(Fabrice... Hum Mutat 2003-04-18

...BRCA2 polymorphisms were used for the haplotype analyses. The markers were located flanking the BRCA2 gene spanning a re...

Italian family with two independent mutations: 3358T/A in BRCA1 and 8756delA ...

Cortesi(Laura),Turchetti(Daniela),Bertoni(... Eur J Hum Genet 2003-11-04

...BRCA2 mutation (8756delA). This BRCA2 mutation was also found in the male breast cancer patient's daughter. The discover...

Defective Brca2 influences topoisomerase I activity in mammalian cells.

Rahden-Staroń(Iwonna),Szumiło(Maria),Grosi... Acta Biochim Pol 2003-12-04

...Brca2 gene or by the transfer of human chromosome 13 providing the BRCA2 gene. These results indicate that the observed ...

Analysis of the G/C polymorphism in the 5'-untranslated region of the RAD51 g...

Blasiak(Janusz),Przybyłowska(Karolina),Cze... Acta Biochim Pol 2003-12-04

...BRCA2 interact with RAD51, a protein essential for maintaining genomic stability by playing a central role in homology-d...

Prediction of pathogenic mutations in patients with early-onset breast cancer...

Lalloo(Fiona),Varley(Jennifer),Ellis(David... Lancet 2003-04-24

We aimed to assess frequency and penetrance of BRCA1, BRCA2,and TP53 mutations in women diagnosed with breast cancer age...

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