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Human gene patents: the possible impacts on genetic services healthcare.

Walpole(Ian R),Dawkins(Hugh J S),Sinden(Pe... Med J Aust 2003-10-07

...BRCA2 could stifle innovation (particularly if other companies adopt similar business models), and are likely to limit t...

Full-length archaeal Rad51 structure and mutants: mechanisms for RAD51 assemb...

Shin(David S),Pellegrini(Luca),Daniels(Dou... EMBO J 2003-10-28

...BRCA2 in higher eukaryotes. A designed P.furiosus RAD51 mutant binds BRC repeats and forms BRCA2-dependent nuclear foci ...

Detection of the most frequent mutations in BRCA1 gene on polyacrylamide gels...

Janatová(M),Pohlreich(P),Matous(B) Neoplasma 2003-11-18

...BRCA2. These results suggest that electrophoresis on Spreadex gels can be used universally for detection of the most fre...

Reproductive factors and ovarian cancer risk in Jewish BRCA1 and BRCA2 mutati...

Modugno(Francesmary),Moslehi(Roxana),Ness(... Cancer Causes Control 2003-12-04

...BRCA2). We obtained data on OC use, childbearing, breastfeeding, gynecologic surgeries and other reproductive factors fr...

Epithelial cancer in Fanconi anemia complementation group D2 (Fancd2) knockou...

Houghtaling(Scott),Timmers(Cynthia),Noll(M... Genes Dev 2003-09-23

...Brca2/Fancd1 hypomorphic mutations. These additional phenotypes were not caused by defects in the ATM-mediated S-phase c...

A novel ubiquitin ligase is deficient in Fanconi anemia.

Meetei(Amom Ruhikanta),de Winter(Johan P),... Nat Genet 2003-12-08

...BRCA2 (refs. 1,2). A key step in this pathway is monoubiquitination of FANCD2, resulting in the redistribution of FANCD2...

[Inherited predisposition to breast cancer: after the BRCA1 and BRCA2 genes, ...

Bonadona(Valérie),Lasset(Christine) Bull Cancer 2003-09-22

Germline mutations of the breast cancer predisposing known genes, BRCA1 and BRCA2, with an autosomal dominant transmissi...

BRCA1 in cancer, cell cycle and genomic stability.

Jhanwar-Uniyal(Meena) Front Biosci 2003-10-24

...BRCA2, p53, Rb and ATM), oncogenes (c-Myc, casein kinase II and E2F), DNA damage repair proteins (RAD50 and RAD51), cell...

Prophylactic surgery in hereditary breast/ovarian cancer syndrome.

Levine(Douglas A),Gemignani(Mary L) Oncology (Williston Park) 2003-11-12

...BRCA2 genes. Reliable screening techniques for these mutations have been developed and are readily available in clinical...

Familial breast cancer and the hCHK2 1100delC mutation: assessing cancer risk...

Varley(Jenny),Haber(Daniel A) Breast Cancer Res 2003-06-27

...BRCA2. The present article describes the published studies on hCHK2 1100delC and addresses some of the key questions rai...

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