Germline mutations in the breast cancer susceptibility genes, BRCA1 and BRCA2, are thought to account for a large portio...
Linkage analysis has identified BRCA1 and BRCA2 germline mutations as the major cause for cancer predisposition in breas...
...BRCA2 germline mutations. We have been unable to show any clearly deleterious mutations but identified four missence mut...
...BRCA2*I2490T/ 5301insA and the other was African American and a compound heterozygote for BRCA2*Q3066X/E1308X. Median ag...
...BRCA2 genes are responsible for a high proportion of familial breast cancer; germline mutations in these genes confer a ...
Fifteen (13.3%) and 21 (18.6%) deleterious germline mutations were identified in BRCA1, and BRCA2 genes among 113 Japane...
Mutations in BRCA1 and BRCA2 confer a high risk of breast and ovarian cancer, but account for only a small fraction of b...
...BRCA2 gene is unknown.,In a Washington DC community-based study conducted in 1996, we tested 5318 Ashkenazi Jews for thr...
...BRCA2 gene. We aimed to assess whether the tumor suppressor gene BRCA2 was the inactivation target for allelic loss obse...
...BRCA2 mRNA levels in tumor tissues was studied in sporadic breast cancer patients. BRCA2 mRNA levels were determined by ...
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