We studied the BRCA2 gene for germline mutations in 71 of 99 patients (72%) with ocular melanoma who were diagnosed cons...
...BRCA2 gene mutation status. This information was used to generate estimates of each woman's risk for breast cancer by us...
...BRCA2 has been suggested to function as a "caretaker" of the genome. Cells without wild-type BRCA2 are deficient in repa...
...BRCA2 mutation and IR exposure on in vivo somatic mutation acquisition, we crossed mice with targeted disruption of Brca...
...BRCA2 gene causes a high risk of developing breast and ovarian cancer. Although the BRCA2 protein has been implicated in...
...BRCA2 genotype and alterations in Smad signaling.
...BRCA2 genes only.,Five patients with PSCP and synchronous EC initially underwent surgical treatment. The remaining two u...
...Brca2 exon 27 that exhibit a moderate decrease in perinatal viability and are fertile. We deleted this Brca2 COOH-termin...
...BRCA2 mutations. Male breast cancer was associated with BRCA2 mutations. The presence of male breast cancer was the only...
...BRCA2 were analyzed in 989 unrelated patients from German breast/ovarian cancer families. A total of 77 BRCA1 and 63 BRC...
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