...BRCA2 gene as well as one systematic study reporting BRCA2 mutations in UM. A single BRCA2 mutation, 6174 del T, occurs ...
...BRCA2) using polymerase chain reaction analysis of polymorphic microsatellite markers. These were compared with 31 patie...
BRCA1 and BRCA2 mutations underlie a substantial proportion of all hereditary breast cancer. The mutational spectrum in ...
...BRCA2 mutation, six of which were novel (Khoo et al., 2000). Knowledge of BRCA gene mutations in the Chinese population ...
...BRCA2 (2586 U/ml), and sporadic (3307 U/ml) cases (P = 0.5). For hereditary cases, optimal cytoreduction was achieved in...
...BRCA2 germline mutations. Needed however, among the physician community, medical geneticists, and genetic counselors, is...
...BRCA2, have established roles in genome integrity maintenance and in the control of homologous recombination. Recent wor...
The relative contribution of heritable and nonheritable factors to disease expression in BRCA2 mutation carriers is larg...
The proportions of mutation of BRCA1 and BRCA2 detected in familial breast cancer vary in different regions. Most breast...
...BRCA2 has been suggested to function as a "caretaker" of the genome. Cells without wild-type BRCA2 are deficient in repa...
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