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TP53 BRCA1 CRISPR single-cell cancer

Armakolas(Athanasios),Ladopoulou(Angela),K... Hum Mutat 2002-02-12

Family history is a well-recognized risk factor for the development of breast cancer. The isolation of BRCA1 and BRCA2 g...

Kraakman-van der Zwet(Maria),Overkamp(Wilh... Mol Cell Biol 2002-01-29

...BRCA2 gene, as well as by the murine Brca2 gene. The Brca2 deficiency in V-C8 cells causes hypersensitivity to various D...

Chinnaiyan(Arul M),Rubin(Mark A) Adv Anat Pathol 2002-02-21

...BRCA2, both of which increase the lifetime risk of developing breast cancer. The genome-wide perspective identified disc...

Chang(J),Elledge(R M) Breast Cancer Res Treat 2002-04-02

There is increasing evidence that BRCA1 and BRCA2 associated tumors may differ from sporadic cancers. The purpose of thi...

Machackova(E),Damborsky(J),Valik(D),Foreto... Hum Mutat 2002-03-07

...BRCA2 genes. In BRCA1, two novel frame shift mutations were identified as 3761-3762delGA and 2616-2617ins10; in BRCA2, t...

Barkardottir(R B),Sarantaus(L),Arason(A),V... Eur J Hum Genet 2002-02-08

The 999del5 mutation is the single, strong BRCA2 founder mutation in Iceland and the most common BRCA1/2 founder mutatio...

Bergman(A),Einbeigi(Z),Olofsson(U),Taib(Z)... Eur J Hum Genet 2002-02-08

...BRCA2 mutation in Sweden is the BRCA1 mutation 3171ins5. In the western part of Sweden this mutation accounts for as muc...

Randall(J),Butow(P),Kirk(J),Tucker(K) Intern Med J 2002-01-10

...BRCA2, now allows women with breast cancer and a family history of breast/ovarian cancer to undergo genetic testing to i...

Pericay(C),Díez(O),Campos(B),Balmaña(J),Do... Med Clin (Barc) 2002-02-25

...BRCA2 cases. The median follow-up in BRCA1 and BRCA2 BC was 131 and 54 months, respectively.,There were no differences i...

Tang(N L),Choy(K W),Pang(C P),Yeo(W),Johns... Clin Chim Acta 2002-01-02

...BRCA2 are high-penetrant cancer predisposition genes, but the prevalence and nature of mutations in these genes appear t...

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