...BRCA2 (P < 0.001). BRCA1 and BRCA2 mutations were twice as common in the presence of a reported second nonovarian cancer...
...BRCA2 genes predispose to a wide spectrum of familial cancers. The functions of the proteins encoded by BRCA1 and BRCA2 ...
...BRCA2 genes--in at least 5% to 10% of all epithelial ovarian cancers. Oral contraceptives are known to reduce the risk f...
...BRCA2 genes, or with strong family histories of breast/ovarian cancer) is a reasonable approach and may result in accept...
...BRCA2 appear to be involved in DNA repair. In particular, the sensitivity of BRCA2-deficient mouse embryonic fibroblasts...
Mutations of BRCA2 in sporadic breast and ovarian carcinomas are exceedingly rare. This led to the suggestion that large...
...BRCA2, which were identified using linkage analysis in large extended breast and/or ovarian cancer pedigrees, are estima...
...BRCA2). A total of four carriers was found (4/225, 1.78%). This frequency is similar to the estimated normal Ashkenazi p...
...BRCA2 might be associated with an increased risk for various GI malignancies. A single mutation (6174delT) occurs in the...
...BRCA2 protein. This study indicates a BRCA2 contribution of 10% (95% CI 2.5-17.5) to our original cohort of 59 breast-ov...
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