...BRCA2. This led us to investigate whether NBS acts as tumor suppressor gene in the development of non-Hodgkin lymphomas....
The BRCA2 tumour suppressor works in DNA recombination and repair pathways to preserve genome integrity. Recent progress...
...BRCA2 genes are frequently mutated. These genes are the two main BC susceptibility genes. BRCA1 predispose to BC and ova...
...BRCA2 expression, in response to cytotoxic agents, may be dependent on p53 status. To investigate this possibility, we q...
...BRCA2 mutations was unexpectedly negative. Their management and the implications of this difficult situation are discuss...
...BRCA2 germ-line mutations than in sporadic breast cancers (odds ratio, 2.8; P = 0.0003). Then, we compared the spectrum ...
...BRCA2, is a largely unexplored area and is seen by some as controversial. The relatively high cumulative risk of second ...
...BRCA2 genes, and the microsatellite loci D13S319 and D13S25, in a series of 25 patients. A further two patients with mye...
...BRCA2. Patient survival and other clinical characteristics of the tumours were compared in patients with BRCA1 or BRCA2 ...
...BRCA2 were screened for mutations in TP53 by single-strand conformation polymorphism analysis.,Antisense inhibition of B...
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