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[Medical management of women with inherited predisposition to breast cancer: ...

Lassetn(C),Bonadona(V) Bull Cancer 2001-09-27

Women identified or suspected as carriers of mutations in BRCA1 or BRCA2 susceptibility genes have a high risk to develo...

Comparison of breast magnetic resonance imaging, mammography, and ultrasound ...

Warner(E),Plewes(D B),Shumak(R S),Catzavel... J Clin Oncol 2001-08-16

Recommended surveillance for BRCA1 and BRCA2 mutation carriers includes regular mammography and clinical breast examinat...

Development of mammary adenocarcinomas by tissue-specific knockout of Brca2 i...

Ludwig(T),Fisher(P),Murty(V),Efstratiadis(... Oncogene 2001-08-30

Cre-mediated deletion of exons 3 and 4 of the mouse Brca2 gene occurring specifically in mammary epithelial cells of con...

Risk of breast and ovarian cancer in women with strong family histories.

Srivastava(A),McKinnon(W),Wood(M E) Oncology (Williston Park) 2001-12-05

...BRCA2, and TP53. Moderate-risk genes associated with syndromes that are inherited in an autosomal dominant pattern (such...

Advances in the management of epithelial ovarian cancer.

Memarzadeh(S),Berek(J S) J Reprod Med 2001-12-07

...BRCA2. Known risk factors for ovarian cancer include nulliparity and a strong family history of ovarian cancer. The use ...

Genetic susceptibility for breast cancer--risk assessment and counseling.

Ang(P),Garber(J E) Semin Oncol 2001-08-30

...BRCA2 mutation carriers, and discuss some of the counseling issues that may occur as physicians and patients explore thi...

Molecular diagnosis of pancreatic cancer.

Inoue(S),Tezel(E),Nakao(A) Hepatogastroenterology 2001-12-19

...BRCA2, microsatellite instability and telomerase. Recent findings which characterize the molecular genetic profile of th...

Mutation analysis of the CHK2 gene in families with hereditary breast cancer.

Allinen(M),Huusko(P),Mäntyniemi(S),Launone... Br J Cancer 2001-08-23

...BRCA2 and TP53 mutations, together explaining about 23% of hereditary predisposition to breast cancer in our country. On...

Analysis of murine Brca2 reveals conservation of protein-protein interactions...

Sarkisian(C J),Master(S R),Huber(L J),Ha(S... J Biol Chem 2001-12-04

...Brca2 locus. We find that murine Brca2 shares multiple properties with human BRCA2 including its regulation during the c...

Sequence, chromosomal location and expression analysis of the murine homologu...

Leasure(C S),Chandler(J),Gilbert(D J),Hous... Gene 2001-08-16

...BRCA2 has provided an insight into the mechanism of how these molecules function as tumor suppressors. Several members o...

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