Germline mutations in BRCA1 and BRCA2 genes predispose to hereditary breast and ovarian cancer. Our aim was to find asso...
...BRCA2 especially for hereditary breast and ovarian cancer, hMLH1 and hMSH2 for hereditary non polyposis colorectal cance...
Many cases of hereditary breast cancer are due to mutations in either the BRCA1 or the BRCA2 gene. The histopathological...
...BRCA2 gene confer susceptibility to breast cancer. Although the function of the BRCA2 protein remains to be determined, ...
...BRCA2 gene by Southern hybridization, with exon 10 and a fragment of exon 11 used as probes. One breast cancer patient w...
...BRCA2 gene alterations (n = 32, ages 28 to 40 years). Among the consecutive patients, extensive LOH was observed for all...
...BRCA2 as well as reproductive history constitute only 30% of the cause, environmental exposure may play a significant ro...
...BRCA2 expression, in response to cytotoxic agents, may be dependent on p53 status. To investigate this possibility, we q...
...Brca2) suppress cancer, at least in part, by participating in DNA damage signaling and DNA repair. Brca1 is hyperphospho...
...BRCA2.,A modest increase in the risk of ovarian cancer (relative risk (RR) = 2.2; 95% confidence interval (CI) = 0.4, 6....
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