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Founder BRCA1 and BRCA2 mutations in early-onset French Canadian breast cance...

Tonin(P N),Perret(C),Lambert(J A),Paradis(... Int J Cancer 2001-05-17

Recently, founder BRCA1 and BRCA2 mutations were identified in Canadian breast cancer and breast-ovarian cancer families...

Breast cancer: hormones and other risk factors.

Hulka(B S),Moorman(P G) Maturitas 2001-06-14

...BRCA2 genes are important correlates of lifetime risk. Genetic polymorphisms associated with estrogen synthesis and meta...

Germline mutations in BRCA1 and BRCA2 in breast-ovarian families from a breas...

Martin(A M),Blackwood(M A),Antin-Ozerkis(D... J Clin Oncol 2001-05-17

...BRCA2 may be as high as 98% depending on the characteristics of the families, suggesting that mutations in BRCA1 or BRCA...

Inhibition of breast and brain cancer cell growth by BCCIPalpha, an evolution...

Liu(J),Yuan(Y),Huan(J),Shen(Z) Oncogene 2001-05-17

BRCA2 is a tumor suppressor gene involved in mammary tumorigenesis. Although important functions have been assigned to a...

International collaboration provides convincing linkage replication in comple...

Cavanaugh(J), Am J Hum Genet 2001-06-07

...BRCA2, most attempts have failed to produce replicable linkage findings. For example, in multiple sclerosis and other co...

Simultaneous breast cancer in non-identical Ashkenazi Jewish twins: managemen...

Sibtain(A),Eeles(R),Wellwood(J),Plowman(P ... Clin Oncol (R Coll Radiol) 2001-05-17

...BRCA2 mutations was unexpectedly negative. Their management and the implications of this difficult situation are discuss...

Psychosocial issues following a positive result of genetic testing for BRCA1 ...

Di Prospero(L S),Seminsky(M),Honeyford(J),... CMAJ 2001-05-03

...BRCA2 genes. The purpose of our study was to explore how genetic testing had affected people found to have a BRCA mutati...

Prevalence and penetrance of germline BRCA1 and BRCA2 mutations in a populati...

Risch(H A),McLaughlin(J R),Cole(D E),Rosen... Am J Hum Genet 2001-04-05

...BRCA2. We specifically tested for 11 of the most commonly reported mutations in the two genes. Then, cases were assessed...

Pseudo-likelihood estimates of the cumulative risk of an autosomal dominant d...

Moore(D F),Chatterjee(N),Pee(D),Gail(M H) Genet Epidemiol 2001-04-05

...BRCA2 was 0.56, a figure that was lower than previously estimated from highly affected families. The method that they us...

Involvement of BRCA1 and BRCA2 in breast cancer in a western Finnish sub-popu...

Pääkkönen(K),Sauramo(S),Sarantaus(L),Vahte... Genet Epidemiol 2001-04-05

...BRCA2 genomic regions. Our haplotype association study did not reveal any founder effects for either BRCA1 or BRCA2. How...

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