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TP53 BRCA1 CRISPR single-cell cancer

Ruiz-Flores(P),Calderón-Garcidueñas(A L),B... Rev Invest Clin 2001-06-28

...BRCA2 genes are frequently mutated. These genes are the two main BC susceptibility genes. BRCA1 predispose to BC and ova...

Nathanson(K L),Wooster(R),Weber(B L),Natha... Nat Med 2001-05-31

...BRCA2, or may represent the cumulative effects of multiple low-penetrance susceptibility alleles. Here we review high- a...

Peshkin(B N),DeMarco(T A),Brogan(B M),Lerm... J Clin Oncol 2001-05-31

Since the cloning of BRCA1 and BRCA2, genetic testing for breast and ovarian cancer susceptibility has become more wides...

Møller(P),Borg(A),Heimdal(K),Apold(J),Vall... Eur J Cancer 2001-06-28

...BRCA2 was found. Approximately, two-thirds of the BRCA1 mutation carriers had one of the four most frequent Norwegian fo...

Takebayashi(Y),Nakayama(K),Kanzaki(A),Miya... Cancer Lett 2001-12-12

...BRCA2 and DCC. Although both microsatellite instability and LOH of NER factors were observed in some cases, there was no...

Pavelić(K),Gall-Troselj(K) J Mol Med (Berl) 2001-12-19

...BRCA2. Breast tumors of patients with germ-line mutations in the BRCA1 and BRCA2 genes have more genetic defects than sp...

Bernard-Gallon(D),Cravello(L),Vissac(C),Bi... Oncol Rep 2001-12-07

BRCA2 is a tumor suppressor gene associated with familial predisposition to breast and ovarian cancer. BRCA2 has been im...

Zweemer(R P),Ryan(A),Snijders(A M),Hermsen... Lab Invest 2001-12-04

The vast majority of familial ovarian cancers harbor a germline mutation in either the breast cancer gene BRCA1 or BRCA2...

Schorge(J O),Mahoney(N M),Miller(D S),Cole... Gynecol Oncol 2001-12-05

...BRCA2 (6174delT) genes. The purpose of this study was to determine the frequency and type of BRCA1-2 mutations in non-As...

Brewster(A),Helzlsouer(K) Curr Opin Oncol 2001-12-26

...BRCA2, prophylactic oophorectomy and bilateral mastectomy have emerged as preventative surgical options that can signifi...

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