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TP53 BRCA1 CRISPR single-cell cancer

Freneaux(P),Stoppa-Lyonnet(D),Mouret(E),Ka... Br J Cancer 2000-12-07

Little data are available concerning the molecular mechanisms of action of Brca1 and Brca2 in breast oncogenesis. Recent...

Goggins(M),Hruban(R H),Kern(S E) Am J Pathol 2000-06-02

Patients harboring germline BRCA2 mutations are at an increased risk of developing pancreatic cancer. We investigated th...

Shen(D),Wu(Y),Subbarao(M),Bhat(H),Chillar(... J Natl Med Assoc 2000-06-20

...BRCA2 genes. The mutations of a breast cancer-susceptible gene, BRCA1, confers increased risk of breast cancer in young ...

Bernard-Gallon(D),Peffault De Latour(M),Ri... Int J Cancer 2000-05-18

...BRCA2 in sporadic breast tumors, we studied the cellular localization and the expression of BRCA2 in carcinomas presenti...

Van Der Looij(M),Szabo(C),Besznyak(I),Lisz... Int J Cancer 2000-06-08

We have investigated the impact of BRCA1 and BRCA2 mutations that were frequently identified among Hungarian high-risk b...

Hamann(H A),Croyle(R T),Venne(V L),Baty(B ... Am J Med Genet 2000-05-24

...BRCA2, along with tests to detect mutations in these genes. Although the appropriateness of BRCA1/2 genetic testing for ...

Lavie(O),Hornreich(G),Ben Arie(A),Renbaum(... Obstet Gynecol 2000-08-02

...BRCA2 germline mutations common in the Jewish population (BRCA1-185delAG and 5382insC, BRCA2-6174delT). In women with ge...

Clark(B A) Cleve Clin J Med 2000-07-12

...BRCA2 genes confer a greatly increased risk of breast cancer, ovarian cancer, and other malignant diseases. This paper o...

Staff(S),Nupponen(N N),Borg(A),Isola(J J),... Genes Chromosomes Cancer 2000-09-14

...BRCA2 (50%) tumors. The majority of BRCA1 and BRCA2 tumors showed a copy number reduction (relative to reference probe w...

Heisey(R E),Carroll(J C),Warner(E),McCread... Can Fam Physician 2000-08-02

...BRCA2 mutation testing. To discuss the implications of identifying patients as BRCA1 or BRCA2 mutation carriers, and to ...

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