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TP53 BRCA1 CRISPR single-cell cancer

Kainu(T),Juo(S H),Desper(R),Schaffer(A A),... Proc Natl Acad Sci U S A 2000-09-19

A significant proportion of familial breast cancers cannot be explained by mutations in the BRCA1 or BRCA2 genes. We app...

Cui(J),Hopper(J L) Cancer Epidemiol Biomarkers... 2000-12-07

...BRCA2 do not report a family history of the disease. That is, the majority of "hereditary" cases are "sporadic." Further...

Theodor(L),Shiri-Sverdlov(R),Yechezkel(G H... Harefuah 2000-08-17

...BRCA2: 67/90 185delAG (BRCA1), 12/90 6174delT (BRCA2), and 4/90 of 5382insC (BRCA1). In addition, a novel mutation in ex...

Arver(B),Du(Q),Chen(J),Luo(L),Lindblom(A) Semin Cancer Biol 2000-10-18

...BRCA2 genes are known to predispose to breast and ovarian cancer in many families. Other genes are only involved in very...

Vazina(A),Baniel(J),Yaacobi(Y),Shtriker(A)... Br J Cancer 2000-08-22

...BRCA2 might be associated with an increased risk for CaP. Three mutations in these two genes (185delAG and 5382InsC (BRC...

Eisinger(F),Alby(N),Bremond(A),Dauplat(J),... Bull Cancer 2000-06-08

...BRCA2 germline mutations. Despite the uncertainty, consensus guidelines were defined to assist practitioners', and patie...

Chang-Claude(J),Becher(H),Caligo(M),Eccles... Dis Markers 2000-01-20

...BRCA2 mutations, using different methods including SSCP, CSGE, DGGE, FAMA and PTT analysis followed by direct sequencing...

Claes(K),Machackova(E),De Vos(M),Poppe(B),... Dis Markers 2000-01-20

Since the identification of the BRCA1 and BRCA2 genes, several hundred different germline mutations in both genes have b...

Frank(T S),Deffenbaugh(A M),Hulick(M),Gump... Dis Markers 2000-01-20

To correlate mutations in BRCA1 and BRCA2 with family history of breast cancer in a first-degree relative for women diag...

De Vos(M),Poppe(B),Delvaux(I),Mortier(G),C... Dis Markers 2000-01-20

...BRCA2 gene has been initiated, is presented. Genetic testing for breast-ovarian cancer susceptibility is offered by a mu...

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