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Zhou(K),Abadie(C),Crivelli(L),Fortin(E),Be... Front Oncol None

...BRCA2 pathogenic variants (PV) and women at high risk without BRCA PV, enrolled in eight cancer genetics units. The stud...

Cimadamore(A),Boixareu(C),Sharp(A),Beltran... Eur Urol 2025-11-00

...BRCA2 and PALB2 biallelic loss). Immune checkpoint inhibitors against PD-1/PD-L1 are effective in hypermutated prostate ...

Deugd(R),Riano(JC),de Vries(E),Cardona(AF)... Diseases 2025-07-18

...BRCA2 (22.3%; 6/27). Similarly, recurrent somatic variants were identified for BRCA1 (82.6%; 38/46) and BRCA2 (17.4%; 8/...

Rungkamoltip(P),Khongcharoen(N),Nokchan(N)... Int J Mol Sci 2025-07-18

BRCA1 and BRCA2 are associated with advanced prostate cancer progression and poor prognosis. Copy number variants (CNVs)...

Dorwal(P),Song(L),Siswara(P),Kumar(A),Robi... J Clin Lab Anal 2025-09-00

...BRCA2, among others, while the PARP-mediated repair pathway is primarily used for single-strand breaks. When a tumour be...

Ho(KC),Huffman(KN),O'Connor(MJ),Sparks(P),... Eplasty 2025-00-00

...BRCA2, CHEK2, PTEN, or PALB2 genes have an increased risk for breast cancer. Hormonal treatment is often used alongside ...

Elmetnawy(W),Nader(H),ElNahas(T),Sabet(S),... Sci Rep 2025-07-18

...BRCA2 LPVs; gBRCA2 c.3139del and c.5690 dup were identified. Variants of uncertain significance (VUS) were found in 22 p...

Huang(CC),Yeh(YC),Tsai(YF),Lin(YS),Chao(TC... Biomed Rep 2025-10-00

...BRCA2 and PALB2. In conclusion, the results indicated that only one-third of actionable mutations could be detected cons...

Dimitrov(G),Popov(E) Clin Genitourin Cancer 2025-10-00

...BRCA2, PALB2, RAD51, FANCD2) versus sensor genes (ATM, ATR, CHEK1, CHEK2, NBS1) in patients with metastatic castration-r...

Vakkalagadda(CV),Bucheit(L),Clemens(K),Sah... Clin Lung Cancer 2025-11-00

Several studies have sought to determine the prevalence of BRCA1/BRCA2 in patient populations, but few have studied impa...