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TP53 BRCA1 CRISPR single-cell cancer

Calaf(G M),Hei(T K) Carcinogenesis 2000-05-22

...BRCA2 and RAD51 expression were detected by immunofluorescence staining and quantified by confocal microscopy. These stu...

Karran(P) Curr Opin Genet Dev 2000-06-05

...BRCA2 genes, which normally confer protection against breast cancer, are involved in homology-directed DSB repair. Defec...

Angèle(S),Hall(J) Mutat Res 2000-06-16

...BRCA2 significantly contribute to familial breast cancer risk, their contribution to sporadic breast cancer is low. In s...

Miron(A),Schildkraut(J M),Rimer(B K),Winer... Ann Surg 2000-06-07

...BRCA2, as observed in a population of breast cancer patients from the southeastern United States, and to examine baselin...

Levy-Lahad(E),Krieger(M),Gottfeld(O),Renba... J Cell Biochem Suppl 2000-07-13

...BRCA2 carriers as potential candidates for breast and ovarian cancer chemoprevention trials. The existence of a large po...

Shen(D),Wu(Y),Subbarao(M),Bhat(H),Chillar(... J Natl Med Assoc 2000-06-20

...BRCA2 genes. The mutations of a breast cancer-susceptible gene, BRCA1, confers increased risk of breast cancer in young ...

Favis(R),Day(J P),Gerry(N P),Phelan(C),Nar... Nat Biotechnol 2000-06-12

...BRCA2 founder mutations in the Ashkenazi Jewish population (BRCA1 185delAG; BRCA1 5382insC; BRCA2 6174delT) as a model s...

Kuschel(B),Aba(F),Lux(M),Jap(D),Bender(H G... Z Arztl Fortbild Qualitatssich 2000-06-01

...BRCA2) are used, but the statistical individual risk assessment still remains uncertain. Calculating an elevated risk or...

Bernard-Gallon(D),Peffault De Latour(M),Ri... Int J Cancer 2000-05-18

...BRCA2 in sporadic breast tumors, we studied the cellular localization and the expression of BRCA2 in carcinomas presenti...

Van Der Looij(M),Szabo(C),Besznyak(I),Lisz... Int J Cancer 2000-06-08

We have investigated the impact of BRCA1 and BRCA2 mutations that were frequently identified among Hungarian high-risk b...

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