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Cytogenetic heterogeneity and clonal evolution in synchronous bilateral breas...

Adeyinka(A),Mertens(F),Bondeson(L),Garne(J... Cancer Genet Cytogenet 2000-04-12

...BRCA2 gene was found on analysis of DNA from peripheral blood lymphocytes. The present findings show that del(16)(q13) i...

BRCA1 and BRCA2 have a limited role in familial prostate cancer.

Sinclair(C S),Berry(R),Schaid(D),Thibodeau... Cancer Res 2000-04-11

...BRCA2 missense mutation and two previously unreported BRCA2 intron polymorphisms. No BRCA1 or BRCA2 truncating mutations...

The Eighth AACR American Cancer Society Award lecture on cancer epidemiology ...

Whittemore(A S) Cancer Epidemiol Biomarkers... 2000-05-12

...BRCA2 mutation carriers, some 30% of these women are estimated to reach age 70 years without developing either cancer. W...

The pathology of familial breast cancer: histological features of cancers in ...

Lakhani(S R),Gusterson(B A),Jacquemier(J),... Clin Cancer Res 2000-06-01

Breast cancers arising in carriers of mutations in the breast cancer susceptibility genes, BRCA1 and BRCA2, differ histo...

The breast cancer susceptibility gene, BRCA2: at the crossroads between DNA r...

Venkitaraman(A R) Philos Trans R Soc Lond B B... 2000-05-18

...BRCA2, has excited much interest in its biological functions. Here, evidence is reviewed that the protein encoded by BRC...

Deletions in the 13q14 locus in adult lymphoblastic leukemia: rate of inciden...

Chung(C Y),Kantarjian(H),Haidar(M),Starost... Cancer 2000-04-27

...BRCA2 genes. Among newly diagnosed patients, LOH was associated with shorter survival (P = 0.007).,These data suggest th...

Frequency of BRCA1/BRCA2 mutations in a population-based sample of young brea...

Malone(K E),Daling(J R),Neal(C),Suter(N M)... Cancer 2000-04-27

There is a clear and growing need for data regarding BRCA1 and BRCA2 mutation frequencies among breast carcinoma cases n...

Reproductive factors in hereditary breast cancer.

Jernström(H C),Johannsson(O T),Loman(N),Bo... Breast Cancer Res Treat 2000-04-11

...BRCA2 negative to serve as a control group. BRCA2 mutation carriers were therefore compared with BRCA1 negative and BRCA...

Frequent deletions at 11q23 and 13q14 in B cell prolymphocytic leukemia (B-PLL).

Lens(D),Matutes(E),Catovsky(D),Coignet(L J... Leukemia 2000-04-07

...BRCA2 was present in 10/18 (55%), 6/18 (33%) and 3/18 (16%) of the cases, respectively. All the cases with D13S25 and BR...

Breast disorders in the pediatric and adolescent patient.

Templeman(C),Hertweck(S P) Obstet Gynecol Clin North A... 2000-03-09

...BRCA2 gene beginning at age 18 to 21 years. All girls with a disorder of breast size or symmetry should be given the opp...

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