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Inherited predisposition to pancreatic adenocarcinoma: role of family history...

Lal(G),Liu(G),Schmocker(B),Kaurah(P),Ozcel... Cancer Res 2000-02-28

...BRCA2 (6174delT)]. The BRCA1 and BRCA2 mutations were identified in Ashkenazi Jewish patients. Four of the mutation carr...

Risk models for familial ovarian and breast cancer.

Antoniou(A C),Gayther(S A),Stratton(J F),P... Genet Epidemiol 2000-04-18

...BRCA2 mutations were estimated to be 0. 00128 and 0.00172, respectively. Our results suggest that BRCA1 and BRCA2 may be...

Insights into the functions of BRCA1 and BRCA2.

Welcsh(P L),Owens(K N),King(M C) Trends Genet 2000-03-08

Since BRCA1 and BRCA2 were cloned five years ago, unraveling their normal functions has posed fascinating problems for c...

The Brca1 and Brca2 proteins and tumor pathogenesis.

Ingvarsson(S) Anticancer Res 2000-02-15

...Brca2. Subsequently, tumors in individuals carrying germline mutation in either BRCA1 or BRCA2 gene show instability at ...

Setting up a breast cancer family history clinic.

Saunders(C),Vijay(V),Stein(J),Baum(M) Ann R Coll Surg Engl 2000-02-22

...BRCA2 gene shortly afterwards. These genes are dominantly inherited with up to 80% penetrance; thus, women (and occasion...

Single-strand conformation polymorphism analysis by capillary and microchip e...

Tian(H),Jaquins-Gerstl(A),Munro(N),Trucco(... Genomics 2000-04-11

...BRCA2, have been identified. In each gene, a small number of specific mutations have been found at relatively high frequ...

Characterization of ten novel and 13 recurring BRCA1 and BRCA2 germline mutat...

De Benedetti(V M),Radice(P),Pasini(B),Stag... Hum Mutat 2000-02-01

...BRCA2 (6.6%). These frequencies indicate that BRCA1/BRCA2 genetic tests should be advised to women with breast cancer di...

Computerized analysis of mammographic parenchymal patterns for breast cancer ...

Huo(Z),Giger(M L),Wolverton(D E),Zhong(W),... Med Phys 2000-03-03

...BRCA2 gene, which confers a very high risk of developing breast cancer. In another approach, the features were related t...

Incidence of malignant tumours in relatives of BRCA1 and BRCA2 germline mutat...

Johannsson(O),Loman(N),Möller(T),Kristoffe... Eur J Cancer 2000-01-04

...BRCA2 associated families from Southern Sweden using data from parish and local tax authorities, as well as the Swedish ...

The candidate tumour suppressor gene, ING1, is retained in colorectal carcino...

Sarela(A I),Farmery(S M),Markham(A F),Guil... Eur J Cancer 2000-01-04

...BRCA2 on chromosome 13q, ING1 appears to be retained intact in colorectal carcinomas.

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