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Differential effects of theaflavin monogallates on cell growth, apoptosis, an...

Lu(J),Ho(C T),Ghai(G),Chen(K Y) Cancer Res 2000-12-22

...BRCA2, and Cox-1, were not significantly affected by TF-2. These findings suggest that TF-2 may be responsible, at least...

In search of the tumour-suppressor functions of BRCA1 and BRCA2.

Scully(R),Livingston(D M) Nature 2000-12-28

...BRCA2 (ref. 1). Each gene product interacts with recombination/DNA repair proteins in pathways that participate in prese...

CYP17 promoter polymorphism and breast cancer in Australian women under age f...

Spurdle(A B),Hopper(J L),Dite(G S),Chen(X)... J Natl Cancer Inst 2000-11-09

...BRCA2, gave a relative hazard in women with the CC genotype of 3.48 (95% CI = 1.13-10.74; P: =.04), which is equivalent ...

[Generic screening for breast cancer].

Ponti(A),Giordano(L) Epidemiol Prev 2000-04-26

...BRCA2 it has been suggested that genetic screening may be of benefit for women at high familial risk. To be able to asse...

An unaffected individual from a breast/ovarian cancer family with germline mu...

Moslehi(R),Russo(D),Phelan(C),Jack(E),Antm... Clin Genet 2000-04-28

Currently many centers offer testing for three specific mutations, 185delAG, 5382insC, and 6174delT, in the BRCA1 and BR...

Nuclear localization signals of the BRCA2 protein.

Yano(K),Morotomi(K),Saito(H),Kato(M),Matsu... Biochem Biophys Res Commun 2000-05-04

BRCA2 is a tumor suppressor gene whose germline mutations increase the lifetime risk of breast cancer. BRCA2 encodes a l...

The BRCA2 activation domain associates with and is phosphorylated by a cellul...

Milner(J),Fuks(F),Hughes-Davies(L),Kouzari... Oncogene 2000-10-19

...BRCA2 is also a binding site for a cellular kinase, although this kinase is distinct from JNK. The BRCA2 associated enzy...

Identification of 12p as a region of frequent deletion in advanced prostate c...

Kibel(A S),Schutte(M),Kern(S E),Isaacs(W B... Cancer Res 1999-01-25

...BRCA2 and PTEN. Twenty RDA clones were generated by comparing genomic DNA from a prostate cancer xenograft to the same p...

Replication error in human breast cancer: comparison with clinical variables ...

Huiping(C),Johannsdottir(J T),Arason(A),Ol... Oncol Rep 1999-03-22

...BRCA2, 999del5 carriers at 43 genomic loci on 13 chromosomes. RER was observed in 8/419 (1.9%) of the cases at one or mo...

Germline PTEN mutations in Cowden syndrome-like families.

Marsh(D J),Dahia(P L),Caron(S),Kum(J B),Fr... J Med Genet 1999-02-04

...BRCA2, and p53, have been associated with familial breast or breast/ovarian cancer families. Given the involvement of PT...

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