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TP53 BRCA1 CRISPR single-cell cancer

Mogilner(A),Otten(M),Cunningham(J D),Browe... Ann Surg Oncol 1999-02-04

The availability of a commercial test for the breast cancer susceptibility genes, BRCA1 and BRCA2, has generated interes...

Osorio(A),Robledo(M),Martínez(B),Cebrián(A... Clin Genet 1999-06-07

The recent isolated gene BRCA2 is responsible for about 45% of familial breast cancer and the majority of male breast ca...

Lee(J S),Wacholder(S),Struewing(J P),McAda... J Natl Cancer Inst 1999-03-04

...BRCA2. To estimate survival differences in the affected relatives according to their BRCA1 and/or BRCA2 mutation carrier...

Vasen(H F),Haites(N E),Evans(D G),Steel(C ... Eur J Cancer 1999-02-25

The recent isolation of breast cancer predisposing genes (BRCA1 and BRCA2) allows the identification of carriers within ...

Bennett(I C),Gattas(M),Teh(B T) Aust N Z J Surg 1999-03-02

...BRCA2, ATM gene, PTEN and p53. Several other less frequently occurring predisposition genes such as the androgen recepto...

Pharoah(P D),Easton(D F),Stockton(D L),Gay... Cancer Res 1999-03-04

The natural history of hereditary and BRCA1- and BRCA2-associated epithelial ovarian cancer may differ from that of spor...

Zou(J P),Hirose(Y),Siddique(H),Rao(V N),Re... Oncol Rep 1999-04-01

...BRCA2a, lacking putative transcriptional activation domain. Both BRCA2a and BRCA2 are expressed at high levels in thymus...

Osin(P),Gusterson(B A),Philp(E),Waller(J),... Eur J Cancer 1999-01-25

...BRCA2. This study was carried out to assess the likely hormone dependence of this group of tumours in comparison with an...

Tirkkonen(M),Kainu(T),Loman(N),Jóhannsson(... Genes Chromosomes Cancer 1999-06-11

...BRCA2 mutation carriers. BRCA2 tumors exhibited a significantly higher number of chromosomal aberrations than sporadic t...

Smith(P D),Crossland(S),Parker(G),Osin(P),... Oncogene 1999-05-19

Inheritance of germ-line mutant alleles of BRCA1 and BRCA2 confers a markedly increased risk of breast cancer and we hav...

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