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TP53 BRCA1 CRISPR single-cell cancer

Goelen(G),Teugels(E),Bonduelle(M),Neyns(B)... J Med Genet 1999-06-10

...BRCA2 gene. Our findings indicate an increased probability of detecting a BRCA gene mutation when ovarian cancer occurre...

Irminger-Finger(I),Siegel(B D),Leung(W C) Biol Chem 1999-06-03

...BRCA2 protein, etc. These proteins likely mediate the involvement of BRCA1 in DNA repair, transcriptional transactivatio...

Zweemer(R P),Verheijen(R H),Menko(F H),Gil... Eur J Obstet Gynecol Reprod... 1999-06-17

...BRCA2 tumoursupressor genes. Patients with hereditary disease do not exhibit pathognomonic features that would allow dis...

Berchuck(A),Carney(M E),Futreal(P A) Eur J Obstet Gynecol Reprod... 1999-06-17

...BRCA2), oophorectomy can now be offered specifically to women who are mutation carriers. Conversely, non-carriers in the...

Stratton(J F),Buckley(C H),Lowe(D),Ponder(... J Natl Cancer Inst 1999-04-20

...BRCA2 mutations in either blood samples or ovarian tissue specimens.,Eleven women had inherited a mutated BRCA1 or BRCA2...

Silva(J M),Gonzalez(R),Provencio(M),Doming... Breast Cancer Res Treat 1999-06-21

...BRCA2 region and those not informative for it, the significance disappeared. In the BRCA2 region, a rate of LOH of 51% w...

Oláh(E) Orv Hetil 1999-05-07

...BRCA2 genes of Hungarian breast/ovarian cancer families will be briefly discussed. These data indicate a strong founder ...

Thompson(L H),Schild(D) Biochimie 1999-06-07

...BRCA2, but also by very high recombination rates in p53-deficient cells.

Geck(P),Szelei(J),Jimenez(J),Sonnenschein(... J Steroid Biochem Mol Biol 1999-05-06

...BRCA2, and centromeric to the retinoblastoma (Rb1) locus. This area is subject to frequent allelic losses in cancers, an...

Eisinger(F),Alby(N),Bremond(A),Dauplat(J),... Ann Genet 1999-05-18

Almost 10% of breast and ovarian cancer are inherited, and the majority are linked to BRCA1 and BRCA2 germline mutations...

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