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TP53 BRCA1 CRISPR single-cell cancer

Abbott(D W),Thompson(M E),Robinson-Benion(... J Biol Chem 1999-07-15

...BRCA2, are responsible for the vast majority of hereditary breast cancer. Although BRCA2 functions to help the cell repa...

Shepel(L A),Gould(M N) Prog Exp Tumor Res 1999-07-15

...BRCA2 in human breast cancer is due to loci that modify the effects of the sensitivity genes. Assuming that human homolo...

Buchholz(T A),Weil(M M),Story(M D),Strom(E... Radiat Oncol Investig 1999-07-12

...BRCA2, or ATM, has been determined to be one mechanism of breast carcinogenesis. It has been established that inherited ...

Noguchi(S),Kasugai(T),Miki(Y),Fukutomi(T),... Cancer 1999-05-27

The purpose of this investigation was to elucidate the clinicopathologic characteristics of BRCA1- and BRCA2-associated ...

Ramus(S J),Bobrow(L G),Pharoah(P D),Finnig... Genes Chromosomes Cancer 1999-06-21

We screened 81 ovarian tumours (30 BRCA1 associated, 18 BRCA2 associated, and 33 sporadic) for somatic TP53 mutations us...

Hyytinen(E R),Frierson(H F),Boyd(J C),Chun... Genes Chromosomes Cancer 1999-06-21

...BRCA2, map to chromosome 13; however, recent reports suggest that unknown genes on 13q are more likely to be involved in...

Gurin(C C),Federici(M G),Kang(L),Boyd(J) Cancer Res 1999-02-10

...BRCA2 genes were generally rare. Four MI+ tumors (29%) contained somatic mutations in the PTEN gene, only one of which w...

Li(S S),Tseng(H M),Yang(T P),Liu(C H),Teng... Hum Genet 1999-05-21

...BRCA2 protein translation. Several genetic polymorphisms in both BRCA1 and BRCA2 genes were also detected in this invest...

Carter(C L),Hailey(B J) Women Health 1999-08-19

...BRCA2 genes. Although still largely limited to research programs, widespread commercial testing and incorporation of gen...

Tengs(T O),Winer(E P),Paddock(S),Aguilar-C... Med Decis Making 1999-08-03

...BRCA2 breast-ovarian cancer susceptibility genes. Prophylactic measures considered included various combinations of imme...

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