Inherited mutations in the genes BRCA1 and BRCA2 are associated with a significantly increased risk of breast cancer, pa...
The frequency of germline BRCA1 and BRCA2 mutations was tested in Yugoslav breast and breast/ovarian cancer families usi...
...BRCA2 and possibly other genes implicated in the repair of double-stranded DNA and in DNA recombination. We investigate ...
We screened 81 ovarian tumours (30 BRCA1 associated, 18 BRCA2 associated, and 33 sporadic) for somatic TP53 mutations us...
...BRCA2, map to chromosome 13; however, recent reports suggest that unknown genes on 13q are more likely to be involved in...
...BRCA2 gene. These data indicate the presence of myeloid- and lymphoid-specific breakpoint cluster regions within chromos...
...BRCA2 and PTEN. We have recently identified a 1-5-cM homozygous deletion on 12p12-13 in a prostate cancer xenograft and ...
...BRCA2, therefore, it appears that LKB1 mutations can cause ovarian tumours when present in the germline, but occur rarel...
...BRCA2 as a predisposition gene. Other more common genes predisposing to ocular melanoma may be of low penetrance. An exa...
...BRCA2 with the RAD51 recombination protein suggested that cancer could arise through defects in recombination. The ident...
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