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Identification of a 3 kb Alu-mediated BRCA1 gene rearrangement in two breast/...

Montagna(M),Santacatterina(M),Torri(A),Men... Oncogene 1999-08-13

...BRCA2 genes; nonetheless, germline mutations of these genes in 'high risk' families are found less frequently than expec...

Genetic testing of breast and ovarian cancer patients: clinical characteristi...

Kaduri(L),Gibs(M),Hubert(A),Sagi(M),Hechin... Eur J Obstet Gynecol Reprod... 1999-09-08

...BRCA2 gene have a substantial life-time risk for breast and ovarian cancers (BC and OC). The aim of the study was to ide...

Germ-line TP53 mutations in Finnish cancer families exhibiting features of th...

Huusko(P),Castrén(K),Launonen(V),Soini(Y),... Cancer Genet Cytogenet 1999-08-18

Mutations in BRCA1 and BRCA2 account for a large portion of the inherited predisposition to breast and ovarian cancer. I...

Progress in cancer genetics: lessons from pancreatic cancer.

Goggins(M),Kern(S E),Offerhaus(J A),Hruban... Ann Oncol 1999-09-09

...BRCA2 gene are present in 5-10% of patients with pancreatic cancer. Typically such patients do not have a family history...

Pathology of incipient pancreatic cancer.

Hruban(R H),Wilentz(R E),Goggins(M),Offerh... Ann Oncol 1999-09-09

...BRCA2.,From these morphologic and molecular observations, we can now develop a progression model for the development of ...

Familial pancreatic cancer.

Hruban(R H),Petersen(G M),Goggins(M),Tersm... Ann Oncol 1999-09-09

...BRCA2 have been shown to predispose to both breast and pancreatic cancer, germline mutations in p16 to melanoma and panc...

Genetic testing for breast-ovarian cancer susceptibility: a regional trial.

Loader(S),Levenkron(J C),Rowley(P T) Genet Test 1999-10-12

...BRCA2 mutations were found in 13 of the 87 families actually tested. If the criteria for testing had been three or more ...

Prevalence of recurring BRCA mutations among Ashkenazi Jewish women with brea...

Robson(M),Dabney(M K),Rosenthal(G),Ludwig(... Genet Test 1999-09-28

The BRCA1 mutations 185delAG and 5382insC and the BRCA2 mutation 6174delT have been detected in a significant proportion...

Mutation testing of early-onset breast cancer genes BRCA1 and BRCA2.

Neuhausen(S L),Ostrander(E A) Genet Test 1999-09-28

BRCA1 and BRCA2, genes predisposing to early-onset breast cancer, have been isolated and are characterized for mutation ...

Genetic testing for breast cancer susceptibility: frequency of BRCA1 and BRCA...

Ganguly(A),Leahy(K),Marshall(A M),Dhulipal... Genet Test 1999-09-28

...BRCA2 gene were detected. We also analyzed 52 Ashkenazi Jewish breast cancer patients for mutations in the BRCA1 and BRC...

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