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High incidence of loss of heterozygosity in breast tumors from carriers of th...

Ingvarsson(S),Geirsdottir(E K),Johannesdot... Cancer Res 1998-11-03

Germ-line mutation in the BRCA2 gene confers an increased risk of breast cancer. An elevation of additional genetic defe...

CpG methylation within the 5' regulatory region of the BRCA1 gene is tumor sp...

Mancini(D N),Rodenhiser(D I),Ainsworth(P J... Oncogene 1998-04-20

...BRCA2. DNA modifications have been shown to occur by a number of mechanisms that include DNA methylation. In some cases,...

Breast cancer risk assessment: use of complete pedigree information and the e...

Schmidt(S),Becher(H),Chang-Claude(J) Hum Genet 1998-04-24

...BRCA2, by likelihood calculations that take into account information from the entire pedigree. This genetic risk was use...

[Genetic predispositions to breast cancer].

Stoppa-Lyonnet(D) Presse Med 1998-04-09

...BRCA2 and BRCA3) have been localized on chromosomes 17 13 and 8. It is highly likely that other genes also have an influ...

Functions of the BRCA1 and BRCA2 genes.

Bertwistle(D),Ashworth(A) Curr Opin Genet Dev 1998-05-21

...BRCA2 genes confer a high risk of breast cancer development. Both genes encode very large proteins of unknown function b...

Analysis of Swedish male breast cancer family data: a simple way to incorpora...

Karunaratne(P M),Elston(R C),Loman(N),Olss... Genet Epidemiol 1998-05-29

...BRCA2 or a mutation in a gene different from BRCA2.

Status of antiestrogen breast cancer prevention trials.

Powles(T J) Oncology (Williston Park) 1998-06-03

...BRCA2. Adverse effects of tamoxifen have been identified, including a transient bone loss in premenopausal women and ute...

[Future developments in genetic research. II. Psychological and social aspects].

Galjaard(H) Ned Tijdschr Geneeskd 1998-07-17

...BRCA2 mutation chose for bilateral mastectomy and oophorectomy. Many questions about psychosocial consequences of predic...

Is hereditary site-specific ovarian cancer a distinct genetic condition?

Liede(A),Tonin(P N),Sun(C C),Serruya(C),Da... Am J Med Genet 1998-02-27

...BRCA2. We consider women from these families to be at increased risk of breast cancer and counsel them accordingly.

Testing for inherited susceptibility to breast cancer: a survey of informed c...

Durfy(S J),Buchanan(T E),Burke(W) Am J Med Genet 1998-02-27

...BRCA2 mutation testing in the United States at this time. We analyzed the content of these forms by developing content c...

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