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TP53 BRCA1 CRISPR single-cell cancer

Lalloo(F),Cochrane(S),Bulman(B),Varley(J),... J Med Genet 1998-03-26

In view of the recent reports of recurrent mutations in BRCA1 and BRCA2 in the Ashkenazi Jewish population, we have unde...

Zweemer(R P),Verheijen(R H),Gille(J J),van... Am J Obstet Gynecol 1998-03-06

Our purpose was to determine the prevalence of BRCA1 and BRCA2 germline mutations among patients from ovarian cancer fam...

Vispé(S),Defais(M) Biochimie 1998-03-11

...BRCA2 implies possible role(s) of this protein in tumorigenesis. Thus, the continued study of Rad51 should bring importa...

Garvin(A M),Attenhofer-Haner(M),Scott(R J) J Med Genet 1998-02-04

...BRCA2, using the protein truncation test (PTT). Nine germline mutations were identified, six in BRCA1 and three in BRCA2...

Lemoine(N R) Digestion 1998-03-11

...BRCA2 gene, while patients with familial pancreatitis due to a mutated cationic trypsinogen gene have a greatly increase...

Finch(M D),Howes(N),Ellis(I),Mountford(R),... Digestion 1998-03-11

...BRCA2 genes, for example, also lead to pancreatic cancer, but the gene responsible for familial pancreatic cancer has no...

Diamond(T M),Sutphen(R),Tabano(M),Fiorica(... Curr Opin Obstet Gynecol 1998-04-27

...BRCA2 genes; however, other genes responsible for inherited susceptibility to these diseases are yet to be identified. A...

Scott(D),Barber(J B),Levine(E L),Burrill(W... Br J Cancer 1998-03-05

...BRCA2, which confer a very high risk of breast cancer and are carried by about 5% of all breast cancer patients, there a...

Li(C),Larsson(C),Futreal(A),Lancaster(J),P... Oncogene 1998-03-06

...BRCA2 and Rb1. This study analysed 13q LOH, DNA ploidy, BRCA2 mutation and pRb expression in prostate cancers. In total,...

Parmigiani(G),Berry(D),Aguilar(O) Am J Hum Genet 1998-03-04

Breast cancer-susceptibility genes BRCA1 and BRCA2 have recently been identified on the human genome. Women who carry a ...

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