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An analysis of age and family history on outcome after breast-conservation tr...

Haas(J A),Schultz(D J),Peterson(M E),Solin... Cancer J Sci Am 1998-12-30

...BRCA2 gene) after breast-conservation treatment.,From 1977 to 1992, 1021 women underwent breast-conservation treatment f...

[Psychological aspects of predictive genetic diagnosis in breast and ovarian ...

Tiefensee(I),Klusmann(D) Psychother Psychosom Med Ps... 1998-12-30

...BRCA2, that predispose women to breast and ovarian cancer were localised in 1990 (Hall et al. 1990, Narod et al. 1991). ...

Germline mutations of the BRCA1 and BRCA2 genes in a breast and ovarian cance...

Randall(T C),Bell(K A),Rebane(B A),Rubin(S... Gynecol Oncol 1998-11-17

...BRCA2 genes. The patient was of Ashkenazi Jewish descent and the BRCA2 mutation was 6174delT, known to be very common in...

A family with three germline mutations in BRCA1 and BRCA2.

Liede(A),Metcalfe(K),Offit(K),Brown(K),Mil... Clin Genet 1998-12-08

Several cancer genetics centres offer testing for specific BRCA1 and BRCA2 mutations to Ashkenazi Jewish individuals wit...

[Is hereditary predisposition to breast cancer linked to BRCA1 a disease of r...

Feunteun(J) C R Seances Soc Biol Fil 1998-11-03

Germline mutations in either the BRCA1 or the BRCA2 gene are responsible for the majority of hereditary breast cancers. ...

Population-based study of risk of breast cancer in carriers of BRCA2 mutation...

Thorlacius(S),Struewing(J P),Hartge(P),Ola... Lancet 1998-11-17

Estimates of an 80-90% risk of breast cancer for carriers of germline mutations in the BRCA1 and BRCA2 genes are based o...

Characterization of BRCA2: temperature sensitivity of detection and cell-cycl...

Su(L K),Wang(S C),Qi(Y),Luo(W),Hung(M C),L... Oncogene 1998-11-16

...BRCA2 was presented in every human cell lines examined, including Capan-1, which expressed a truncated BRCA2 due to a BR...

The BRCA2 gene product functionally interacts with p53 and RAD51.

Marmorstein(L Y),Ouchi(T),Aaronson(S A) Proc Natl Acad Sci U S A 1998-12-16

...BRCA2 expression in cancer cells inhibits p53's transcriptional activity, and RAD51 coexpression enhances BRCA2's inhibi...

BRCA2 associates with acetyltransferase activity when bound to P/CAF.

Fuks(F),Milner(J),Kouzarides(T) Oncogene 1998-12-10

...BRCA2 has transcriptional activation potential conferred by its amino-terminal third exon. Here, we show that BRCA2 inte...

Conservation of function and primary structure in the BRCA1-associated RING d...

Ayi(T C),Tsan(J T),Hwang(L Y),Bowcock(A M)... Oncogene 1998-11-19

...BRCA2. Moreover, murine Bard1 retains the ability to associate in vivo with BRCA1, and its expression pattern in adult m...

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