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TP53 BRCA1 CRISPR single-cell cancer

Crook(T),Brooks(L A),Crossland(S),Osin(P),... Oncogene 1998-11-17

The status of p53 was investigated in breast tumours arising in germ-line carriers of mutant alleles of BRCA1 and BRCA2 ...

Ingvarsson(S),Geirsdottir(E K),Johannesdot... Cancer Res 1998-11-03

Germ-line mutation in the BRCA2 gene confers an increased risk of breast cancer. An elevation of additional genetic defe...

Chen(J),Hedman(M Z),Arver(B W),Sigurdsson(... Eur J Hum Genet 1998-10-27

...BRCA2) are believed to be responsible for a significant fraction of hereditary breast cancer. To determine the BRCA2 mut...

Lynch(B J),Holden(J A),Buys(S S),Neuhausen... Hum Pathol 1998-11-05

...BRCA2 tumor suppressor genes and compared them with a group of 20 breast cancer patients with non-HBC. In general, patie...

Iglehart(J D),Miron(A),Rimer(B K),Winer(E ... Ann Surg 1998-10-14

...BRCA2 testing results.,This study examines estimates of carrying BRCA1 and BRCA2 mutations among women participating in ...

Lehrer(S),Fodor(F),Stock(R G),Stone(N N),E... Br J Cancer 1998-09-22

...BRCA2. There was a significant difference in the incidence of the BRCA1 and BRCA2 mutations in the breast and prostate c...

Tonin(P N),Mes-Masson(A M),Futreal(P A),Mo... Am J Hum Genet 1998-12-23

We have identified four mutations in each of the breast cancer-susceptibility genes, BRCA1 and BRCA2, in French Canadian...

Watanabe(M),Shiraishi(T),Muneyuki(T),Nagai... Oncology 1998-12-11

...BRCA2. Frequent loss of heterozygosity was observed for D8S201 (48%), LPL (48%), and DCC (26%). In contrast, the inciden...

Chen(J),Silver(D P),Walpita(D),Cantor(S B)... Mol Cell 1998-11-02

BRCA1 and BRCA2 account for most cases of familial, early onset breast and/or ovarian cancer and encode products that ea...

Sobottka(S B),Frank(S),Hampl(M),Schackert(... Acta Neurochir (Wien) 1998-09-28

...BRCA2, DCC, and MCC). Furthermore, no mutations were found in the constitutional DNA of either twin sister or in the DNA...

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