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Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in...

Ford(D),Easton(D F),Stratton(M),Narod(S),G... Am J Hum Genet 1998-04-23

...BRCA2. Conversely, the majority of families with male and female breast cancer were due to BRCA2 (76%). The largest prop...

BRCA2 and p53 mutations in primary breast cancer in relation to genetic insta...

Gretarsdottir(S),Thorlacius(S),Valgardsdot... Cancer Res 1998-03-25

...BRCA2 and p53 mutations in tumors. p53 mutations are more frequent in BRCA2 mutation carriers than they are in controls....

An interstitial tandem duplication of 9p23-24 coexists with a mutation in the...

Savelyeva(L),Claas(A),Gier(S),Schlag(P),Fi... Cancer Res 1998-03-25

...BRCA2 mutation may be augmenting the risk of male breast cancer conferred by the BRCA2 mutation.

An evaluation of common breast cancer gene mutations in a population of Ashke...

Lalloo(F),Cochrane(S),Bulman(B),Varley(J),... J Med Genet 1998-03-26

In view of the recent reports of recurrent mutations in BRCA1 and BRCA2 in the Ashkenazi Jewish population, we have unde...

Epidemiology, prevention, and early detection of breast cancer.

Alberg(A J),Helzlsouer(K J) Curr Opin Oncol 1998-01-06

...BRCA2 mutations may be less than previously estimated. Antiestrogens with lesser risks than tamoxifen hold promise for c...

Low proportion of BRCA1 and BRCA2 mutations in Finnish breast cancer families...

Vehmanen(P),Friedman(L S),Eerola(H),McClur... Hum Mol Genet 1998-03-18

...BRCA2 gene were now analyzed for mutations in the BRCA1 gene. The coding region and splice boundaries of BRCA1 were anal...

Molecular advances in pancreatic cancer.

Lemoine(N R) Digestion 1998-03-11

...BRCA2 gene, while patients with familial pancreatitis due to a mutated cationic trypsinogen gene have a greatly increase...

Hereditary pancreatitis and familial pancreatic cancer.

Finch(M D),Howes(N),Ellis(I),Mountford(R),... Digestion 1998-03-11

...BRCA2 genes, for example, also lead to pancreatic cancer, but the gene responsible for familial pancreatic cancer has no...

Prognostic value of loss of heterozygosity at BRCA2 in human breast carcinoma...

Bièche(I),Noguès(C),Rivoilan(S),Khodja(A),... Br J Cancer 1998-01-08

...BRCA2 status (P = 0.34, P = 0.29 respectively). LOH at BRCA2 does not therefore appear to be a major prognostic marker i...

Germline BRCA2 mutations in men with breast cancer.

Mavraki(E),Gray(I C),Bishop(D T),Spurr(N K... Br J Cancer 1998-01-08

...BRCA2 mutations; two frameshifts and one putative missense mutation were identified. One of the frameshifts was detected...

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