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Oral contraceptives and the risk of hereditary ovarian cancer. Hereditary Ova...

Narod(S A),Risch(H),Moslehi(R),Dørum(A),Ne... N Engl J Med 1998-08-13

Women with mutations in either the BRCA1 or the BRCA2 gene have a high lifetime risk of ovarian cancer. Oral contracepti...

[Diagnostic molecular biology in breast cancer].

Andersen(T I),Børresen-Dale(A L) Tidsskr Nor Laegeforen 1998-08-11

...BRCA2 are particularly prone to develop breast cancer. Genetic screening and counselling programs have been established ...

Molecular genetic characterization of BRCA1- and BRCA2-linked hereditary ovar...

Rhei(E),Bogomolniy(F),Federici(M G),Maresc... Cancer Res 1998-08-27

Hereditary ovarian cancers associated with germline mutations in either BRCA1 or BRCA2 were studied to determine whether...

Cells deleted for Brca2 COOH terminus exhibit hypersensitivity to gamma-radia...

Morimatsu(M),Donoho(G),Hasty(P) Cancer Res 1998-08-27

...Brca2-MmRad51 interaction is analyzed in mouse cells deleted for the COOH terminus of Brca2 (amino acids 3140-3328), whi...

Current perspectives on radiation-induced breast cancer.

Goss(P E),Sierra(S) J Clin Oncol 1998-01-27

...BRCA2 genes, the p53 gene, the ataxia telangiectasia (AT) gene, and other nonspecific alterations in DNA repair proficie...

Hereditary and sporadic ovarian cancer: genetic testing and clinical implicat...

Angioli(R),Estape(R),Mason(M),Penalver(M) Int J Oncol 1998-06-02

...BRCA2. Malfunction of the protein products of these genes have also been found to be involved in sporadic ovarian cancer...

Differential transcriptional activation by the N-terminal region of BRCA1 spl...

Cui(J Q),Wang(H),Reddy(E S),Rao(V N) Oncol Rep 1998-05-01

...BRCA2 proteins were shown to function as transactivation domains when fused to GAL4 DNA binding domain. We have recently...

Inherited BRCA2 mutation associated with high grade breast cancer.

Agnarsson(B A),Jonasson(J G),Björnsdottir(... Breast Cancer Res Treat 1998-04-21

...BRCA2 mutation are high grade tumors with a rapid proliferation rate. Other or additional factors than the defining BRCA...

Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in...

Ford(D),Easton(D F),Stratton(M),Narod(S),G... Am J Hum Genet 1998-04-23

...BRCA2. Conversely, the majority of families with male and female breast cancer were due to BRCA2 (76%). The largest prop...

High incidence of loss of heterozygosity at chromosome 17p13 in breast tumour...

Eiriksdottir(G),Barkardottir(R B),Agnarsso... Oncogene 1998-03-02

Breast tumours from BRCA1 and BRCA2 mutation carriers are genetically instable and display specific patterns of chromoso...

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