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TP53 BRCA1 CRISPR single-cell cancer

Teague(K E),Brown(J A),Meyer(J M),Kahn(M J... J Cancer Educ 1997-05-02

...BRCA2, clinical testing for detection of the mutated genes may be available in the near future. Primary care physicians ...

Hopper(J L) Aust N Z J Public Health 1997-02-19

Two genes associated with a high breast cancer risk (BRCA1 and BRCA2) have been discovered recently from study of large ...

Gayther(S A),Mangion(J),Russell(P),Seal(S)... Nat Genet 1997-01-28

...BRCA2 on chromosome 13q12-13 has recently been identified. Germline mutations of BRCA2 are predicted to account for appr...

Dunning(A M),Chiano(M),Smith(N R),Dearden(... Hum Mol Genet 1997-08-27

...BRCA2. However, these mutations are uncommon in the population and they probably account for only a few percent of all b...

Connor(F),Smith(A),Wooster(R),Stratton(M),... Hum Mol Genet 1997-08-27

...Brca2 protein and this has revealed that, like Brca1, Brca2 is relatively poorly conserved between humans and mice. Brca...

Tsukamoto(K),Emi(M),Nakamura(Y) Nihon Rinsho 1997-02-24

...BRCA2, have been isolated. These findings enable to use these genes for genetic diagnosis in clinical oncology.

Lynch(H T),Lynch(J F) Curr Probl Cancer 1997-04-04

...BRCA2 genes, if a first-degree relative in direct genetic lineage had hereditary breast cancer or hereditary breast-ovar...

Gayther(S A),Ponder(B A) Mol Med Today 1997-06-25

Two cancer susceptibility genes, BRCA1 on chromosome 17q12-21 and BRCA2 on chromosome 13q12-13, are thought to be respon...

Sharan(S K),Morimatsu(M),Albrecht(U),Lim(D... Nature 1997-05-22

...Brca2-deficient embryos, their radiation sensitivity, and the association of Brca2 with Rad51 indicate that Brca2 may be...

Rajan(J V),Marquis(S T),Gardner(H P),Chodo... Dev Biol 1997-06-02

...Brca2. These observations imply that Brca1 and Brca2 mRNA expression are differentially regulated by sex hormones. In or...

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