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Whitcomb(DC) Curr Opin Gastroenterol 2025-09-01

...BRCA2 mutations). Polygenic risk scores (PRS) combined with clinical markers like new-onset diabetes (NOD) increase the ...

Anagho-Mattanovich(HA),Mullari(M),Anagho-M... Mol Cell Proteomics 2025-08-00

...BRCA2 mutation was not reverted. However, we observed increased expression of Fanconi anemia group D2 (FANCD2), histone ...

Shi(Q),Gao(J),Yu(H),Niu(Y),Yuan(E),Guo(Y),... Transl Oncol 2025-09-00

...BRCA2 p.W2619C and BRCA2 p.N1023_I1024del variants. Functional assays demonstrated that the BRCA2 p.W2619C variant signi...

Yoon(CE),Kang(S),Rhew(SA),Kwon(HJ),Shin(D)... BMC Urol 2025-07-14

...BRCA2, BCL6, and CHEK2 were significant predictors for BCR. CONCLUSION: Our findings suggest that specific genetic mutat...

Noman(AM),Sultan(MT),Raza(H),Imran(M),Huss... Food Sci Nutr 2025-07-00

...BRCA2 expression. Combining Naringenin with other bioactive compounds, chemotherapy drugs, and nanoformulations is a nov...

Obispo(B),Bailleux(C),Cantos(B),Zamora(P),... Cancers (Basel) 2025-07-30

...BRCA2), (gBRCAm), who are typically young women, often require more aggressive therapeutic interventions. These mutation...

Kumari(R),Banerjee(S) BMC Mol Cell Biol 2025-07-30

...BRCA2, and BAX, along with other apoptotic genes involved in tumorigenesis, apoptosis, and drug resistance. Targeting th...

Colin-Leitzinger(C),Lawson-Michod(KA),John... Clin Epigenetics 2025-07-30

...BRCA2 mutations. Two RE methylation clusters were identified. Cluster 1 exhibited a more hypomethylated RE profile ("Act...

Wong(K),Kameoka(A),Fukui(JA) Ther Adv Med Oncol 2025-00-00

...BRCA2 mutations), <40 years old at diagnosis, or history of breast cancer recurrence-were offered tumor-informed ctDNA a...

Maagdenberg(AM),Vledder(A),Paijens(ST),Pla... BJC Rep 2025-07-08

...BRCA2 mutation, primary treatment, and surgical outcome are strong independent prognostic factors of overall survival. O...