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TP53 BRCA1 CRISPR single-cell cancer

Connor(F),Bertwistle(D),Mee(P J),Ross(G M)... Nat Genet 1997-12-29

...Brca2 in mice. Unlike other mutations in the Brca2 gene, which are lethal early in embryogenesis when homozygous, some o...

Jhappan(C),Morse(H C),Fleischmann(R D),Got... Nat Genet 1997-12-29

...BRCA2 (ref. 15).

Wang(S C),Lin(S H),Su(L K),Hung(M C) Biochem Biophys Res Commun 1997-06-24

...BRCA2 can predispose an individual to develop breast cancer. We investigated the expression of both BRCA2 and BRCA1 duri...

Mizuta(R),LaSalle(J M),Cheng(H L),Shinohar... Proc Natl Acad Sci U S A 1997-07-21

...BRCA2, the homologue of the second breast cancer susceptibility gene protein in humans, demonstrating an in vitro associ...

Lancet 1997-06-24

...BRCA2-mutation carriers (3%) or controls (2%). Tubular carcinoma was less common in BRCA2-mutation carriers. The few muc...

Xu(C F),Chambers(J A),Nicolai(H),Brown(M A... Genes Chromosomes Cancer 1997-04-23

...BRCA2 regions were performed on 33 families, and mutations in the BRCA1 gene were identified in all but one family that ...

Greene(M H) Mayo Clin Proc 1997-01-29

...BRCA2, p53, and the Cowden disease gene are relatively uncommon, are highly penetrant, and produce striking familial clu...

Daudt(A),Alberg(A J),Helzlsouer(K J) Curr Opin Oncol 1997-04-04

...BRCA2, that may account for a majority of inherited forms of breast cancer cases. Hypotheses have been formulated concer...

Bignell(G),Micklem(G),Stratton(M R),Ashwor... Hum Mol Genet 1997-03-26

The breast cancer susceptibility gene BRCA2 encodes a protein of 3418 amino acids which does not exhibit substantial seq...

Flanders(T Y),Foulkes(W D) J Med Genet 1997-03-13

...BRCA2, and APC. This highlights the need for a full family history in apparently sporadic cases. Somatic mutations in p1...

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