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TP53 BRCA1 CRISPR single-cell cancer

Rohlfs(E M),Learning(W G),Friedman(K J),Co... Clin Chem 1997-01-30

...BRCA2, which confer increased susceptibility to breast and (or) ovarian cancer, were recently identified. Mutation analy...

Beckmann(M W),Schnürch(H G),Bodden-Heidric... Eur J Cancer Prev 1997-06-26

...BRCA2, has given insight into the genetic background of part of the familial breast/ovarian cancer syndromes. This has l...

Kerangueven(F),Eisinger(F),Noguchi(T),Alli... Oncogene 1997-02-27

...BRCA2 and Rb1 genes, this work allowed to distinguish a total of 12 regions of LOH, variably affected in breast tumors a...

Garcia-Marco(J A),Price(C M),Catovsky(D) Cancer Genet Cytogenet 1997-04-10

...BRCA2) and 13q14 (RB1 and DBM locus) were used in 35 cases. Twenty-eight (80%) cases showed deletion of a 1Mb 13q12.3 en...

Tirkkonen(M),Johannsson(O),Agnarsson(B A),... Cancer Res 1997-04-17

BRCA1 and BRCA2 mutations confer increased risk for development of breast cancer, but a number of additional, currently ...

Sharan(S K),Bradley(A) Genomics 1997-04-24

...BRCA2 gene are responsible for about 45% of hereditary early onset breast cancer. Recently, the human BRCA2 gene was clo...

Schubert(E L),Lee(M K),Mefford(H C),Argonz... Am J Hum Genet 1997-06-03

...BRCA2 mutations in American families--particularly the appearance in America of European founder mutations--the BRCA2 co...

Vehmanen(P),Friedman(L S),Eerola(H),Sarant... Am J Hum Genet 1997-06-03

...BRCA2 gene. Eight families (8%) were found to carry five different mutations, all of which are predicted to prematurely ...

Levy-Lahad(E),Catane(R),Eisenberg(S),Kaufm... Am J Hum Genet 1997-06-03

...BRCA2 6174delT (hazard ratio 2.1 [95% CI 1.2-3.8]; two-tailed P = .01). Thus, the high rate of germ-line BRCA1/BRCA2 mut...

Håkansson(S),Johannsson(O),Johansson(U),Se... Am J Hum Genet 1997-06-03

...BRCA2 mutations were detected in 12 families, of which 3 contained cases of male breast cancer. One BRCA2 mutation, 4486...

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