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Risk factors for non-invasive lesions of the fallopian tube in BRCA mutation ca…

Vicus(Danielle),Shaw(Patricia A),Finch(Amy),… Gynecol Oncol 2010-09-01

To identify risk factors for the presence of a non-invasive lesion of the fallopian tube in women with a BRCA1 or BRCA2 ...

Evaluation of the contribution of the three breast cancer susceptibility genes …

Guénard(Frédéric),Pedneault(Christopher St-L… Genet Test Mol Biomarkers 2010-12-06

...BRCA1 and BRCA2. Monoallelic PALB2 truncating mutations were shown to confer higher risk of breast cancer. To evaluate t...

Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1.

Nakada(Shinichiro),Tai(Ikue),Panier(Stephani… Nature 2010-10-08

...BRCA1-dependent regulatory ubiquitination. Here we report that OTUB1, a deubiquitinating enzyme, is an inhibitor of DSB-...

Loss of H3 K79 trimethylation leads to suppression of Rtt107-dependent DNA dama…

Lévesque(Nancy),Leung(Grace P),Fok(Alexandra… J Biol Chem 2010-11-30

...BRCA1 C-terminal domain-containing protein Rtt107/Esc4 is required for restart of DNA replication after successful repai...

A critical re-appraisal of BRCA1 methylation studies in ovarian cancer.

Senturk(Emir),Cohen(Samantha),Dottino(Peter … Gynecol Oncol 2010-10-20

...BRCA1 status of tumors. Mutations in the BRCA1 gene have long been known to increase a woman's risk of developing ovaria...

The rate of the predominant Jewish mutations in the BRCA1, BRCA2, MSH2 and MSH6…

Barak(Frida),Milgrom(Roni),Laitman(Yael),Gem… Gynecol Oncol 2010-11-24

...BRCA1 MSH6 or MSH2 mutations.,Our data do not support screening for BRCA1/2 mutations in consecutive EC patients.

Loss of BRCA1 leads to an increased sensitivity to Bisphenol A.

Jones(Laundette P),Sampson(Aishia),Kang(Hyo … Toxicol Lett 2010-12-17

...BRCA1 enhances BPA-induced cell proliferation in both systems. In vitro, we found that loss of BRCA1 enhances BPA-induce...

Absence of CHEK2*1100delC mutation in families with hereditary breast cancer in…

Iniesta(Maria D),Gorin(Michael A),Chien(Ling… Cancer Genet Cytogenet 2010-10-12

...BRCA1/2 at the University of Michigan Comprehensive Cancer Center. We genotyped 102 members from 90 families for CHEK2*1...

A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and …

Antoniou(Antonis C),Wang(Xianshu),Fredericks… Nat Genet 2010-10-28

...BRCA1 mutations who were diagnosed with invasive breast cancer under age 40 and 1,190 BRCA1 carriers without breast canc...

Common variants at 19p13 are associated with susceptibility to ovarian cancer.

Bolton(Kelly L),Tyrer(Jonathan),Song(Honglin… Nat Genet 2010-10-28

...BRCA1-interacting gene C19orf62, also known as MERIT40, which contains rs8170, in EOC development.

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