...BRCA2, and APC. This highlights the need for a full family history in apparently sporadic cases. Somatic mutations in p1...
...BRCA2, that may account for a majority of inherited forms of breast cancer cases. Hypotheses have been formulated concer...
...BRCA2, p53, and the DNA mismatch repair genes.
...BRCA2. Inactivating mutations have been found throughout both genes, and the majority are predicted to result in truncat...
...BRCA2 genes.,A task force with expertise in medical genetics, oncology, primary care, gastroenterology, and epidemiology...
BRCA1 and BRCA2 mutations confer increased risk for development of breast cancer, but a number of additional, currently ...
...BRCA2) and 13q14 (RB1 and DBM locus) were used in 35 cases. Twenty-eight (80%) cases showed deletion of a 1Mb 13q12.3 en...
...BRCA2. However, these mutations are uncommon in the population and they probably account for only a few percent of all b...
...Brca2 protein and this has revealed that, like Brca1, Brca2 is relatively poorly conserved between humans and mice. Brca...
...BRCA2, has given insight into the genetic background of part of the familial breast/ovarian cancer syndromes. This has l...
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