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Pancreatic adenocarcinoma: epidemiology and genetics.

Flanders(T Y),Foulkes(W D) J Med Genet 1997-03-13

...BRCA2, and APC. This highlights the need for a full family history in apparently sporadic cases. Somatic mutations in p1...

Epidemiology, prevention, and early detection of breast cancer.

Daudt(A),Alberg(A J),Helzlsouer(K J) Curr Opin Oncol 1997-04-04

...BRCA2, that may account for a majority of inherited forms of breast cancer cases. Hypotheses have been formulated concer...

Hereditary ovarian cancer.

Langston(A A),Ostrander(E A) Curr Opin Obstet Gynecol 1997-06-24

...BRCA2, p53, and the DNA mismatch repair genes.

The BRCA1 and BRCA2 breast cancer genes.

Casey(G) Curr Opin Oncol 1997-09-25

...BRCA2. Inactivating mutations have been found throughout both genes, and the majority are predicted to result in truncat...

Recommendations for follow-up care of individuals with an inherited predispos...

Burke(W),Daly(M),Garber(J),Botkin(J),Kahn(... JAMA 1997-04-04

...BRCA2 genes.,A task force with expertise in medical genetics, oncology, primary care, gastroenterology, and epidemiology...

Distinct somatic genetic changes associated with tumor progression in carrier...

Tirkkonen(M),Johannsson(O),Agnarsson(B A),... Cancer Res 1997-04-17

BRCA1 and BRCA2 mutations confer increased risk for development of breast cancer, but a number of additional, currently ...

Interphase cytogenetics in chronic lymphocytic leukemia.

Garcia-Marco(J A),Price(C M),Catovsky(D) Cancer Genet Cytogenet 1997-04-10

...BRCA2) and 13q14 (RB1 and DBM locus) were used in 35 cases. Twenty-eight (80%) cases showed deletion of a 1Mb 13q12.3 en...

Common BRCA1 variants and susceptibility to breast and ovarian cancer in the ...

Dunning(A M),Chiano(M),Smith(N R),Dearden(... Hum Mol Genet 1997-08-27

...BRCA2. However, these mutations are uncommon in the population and they probably account for only a few percent of all b...

Cloning, chromosomal mapping and expression pattern of the mouse Brca2 gene.

Connor(F),Smith(A),Wooster(R),Stratton(M),... Hum Mol Genet 1997-08-27

...Brca2 protein and this has revealed that, like Brca1, Brca2 is relatively poorly conserved between humans and mice. Brca...

Early cancer detection programmes for women at high risk for breast and ovari...

Beckmann(M W),Schnürch(H G),Bodden-Heidric... Eur J Cancer Prev 1997-06-26

...BRCA2, has given insight into the genetic background of part of the familial breast/ovarian cancer syndromes. This has l...

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